SKINDERMA Lipase 5 x 10ml vials

SKINDERMA Lipase 5 x 10ml is a professional enzyme-based lipolytic mesotherapy solution that targets and breaks down stored localized fat. Lipase acts directly on triglycerides, dissolving fat molecules into smaller components that the body can more easily mobilize and eliminate — delivering visible volume reduction with minimal irritation or discomfort.

Key Benefits

• Breaks down fat molecules (triglycerides) into smaller, easily mobilized components
• Reduces localized fat deposits and body volume
• Gentle enzymatic mechanism minimizes irritation and discomfort
• Does not cause damage to surrounding tissue
• Ideal for targeted fat reduction protocols

Active Ingredients

• Lipase — a naturally occurring fat-digesting enzyme that catalyzes the hydrolysis of triglycerides stored in adipocytes into free fatty acids and glycerol. Unlike chemical sclerosing agents (such as Phosphatidylcholine or Sodium Deoxycholate) which disrupt cell membranes, Lipase works through a purely enzymatic mechanism — selectively breaking down fat molecules without damaging surrounding tissue. The released fatty acids and glycerol are then transported through the lymphatic system for metabolic elimination, resulting in visible reduction of fat volume and body contour improvement.
• Mannitol — a sugar alcohol that acts as an antioxidant and free radical scavenger in the treated tissue, reducing oxidative stress and supporting formulation stability. It also helps minimize post-treatment discomfort and tissue reaction.
• Aqua (Water) — sterile carrier base ensuring biocompatibility and formulation stability.

Treatment Area: Body
Recommended For: Fat and volume reduction, localized fat deposits
Presentation: 5 x 10ml vials

What is SKINDERMA Lipase and how does it dissolve fat? SKINDERMA Lipase is a professional enzyme-based lipolytic mesotherapy solution containing Lipase — a fat-digesting enzyme that catalyzes the hydrolysis of triglycerides in adipocytes into free fatty acids and glycerol. Unlike chemical sclerosing lipolytic agents, Lipase works through a purely enzymatic mechanism, selectively targeting fat molecules without disrupting surrounding tissue. The released components are then cleared via the lymphatic system for metabolic elimination.

How is Lipase mesotherapy different from Phosphatidylcholine? Phosphatidylcholine and Sodium Deoxycholate work by disrupting the cell membrane of adipocytes, causing them to lyse and release stored fat — a more aggressive mechanism that can cause significant swelling and discomfort. Lipase, by contrast, enzymatically digests triglycerides without destroying the cell membrane, making it a gentler alternative with a lower likelihood of post-treatment irritation, bruising, and tissue reaction — while still delivering effective fat reduction.

What areas can be treated with Lipase mesotherapy? Common treatment areas include the abdomen, flanks, inner and outer thighs, arms, knees, back fat, and other areas of localized fat accumulation. Its gentle mechanism also makes it suitable for more sensitive areas where aggressive lipolytic agents may not be appropriate.

Who is this product for? SKINDERMA Lipase is formulated for licensed aesthetic practitioners, dermatologists, and body contouring specialists performing enzymatic lipolytic mesotherapy protocols. 

For professional use only. Not intended to diagnose, treat, cure, or prevent any disease.