SKINDERMA EXO-HAIR EXOSOME 5 x 10ml

SKINDERMA EXO-HAIR 5 x 10ml is a remarkable advancement in aesthetic hair restoration, developed to address hair loss and promote exceptional hair rejuvenation through the next generation of exosome-based scalp mesotherapy/microneedling. This professional-grade formula incorporates a unique synergy of plant- and microbiome-derived extracellular vesicles and targeted bioactive ingredients, delivering regenerative signals directly to hair follicle cells to stimulate growth, strengthen roots, and restore scalp vitality.

Ideal for aesthetic professionals performing scalp mesotherapy and microneedling hair restoration protocols for androgenic alopecia, diffuse hair loss, and hair thinning.

Key Benefits

• Stimulates hair follicle activity and promotes hair regrowth via exosome signaling
• Addresses androgenic alopecia and diffuse hair loss
• Restores scalp microbiome balance for a healthier follicle environment
• Strengthens hair roots and reduces shedding
• Revitalizes and nourishes the scalp at the cellular level
• Supports improved hair density and thickness over a course of treatments

Active Ingredients

• Lactobacillus Extracellular Vesicles (Postbiotic Exosomes) — nano-sized extracellular vesicles derived from Lactobacillus probiotic bacteria, representing the cutting edge of postbiotic technology in scalp aesthetics. The scalp microbiome — the diverse ecosystem of bacteria, fungi, and other microorganisms that colonize the scalp skin — plays a critical and increasingly recognized role in follicle health. Dysbiosis (microbial imbalance) of the scalp microbiome is associated with chronic scalp inflammation, elevated Malassezia colonization, sebaceous gland disruption, and impaired follicle cycling — all of which contribute to hair loss progression. Lactobacillus-derived EVs carry postbiotic signaling molecules (including bacteriocins, short-chain fatty acids, and anti-inflammatory peptides) that modulate the scalp immune environment, reduce Th1/Th17-driven perifollicular inflammation, support the restoration of a balanced microbiome, and create the optimal anti-inflammatory scalp environment for follicle regeneration. Unlike live probiotics, EVs are cell-free and stable, providing the beneficial signaling of Lactobacillus without the need for viable bacteria.
• Galactomyces Extracellular Vesicles (Ferment-Derived Exosomes) — extracellular vesicles derived from Galactomyces ferment, a yeast-origin fermentation byproduct with a well-established track record in professional skin and scalp care. Galactomyces fermentation produces a rich cargo of vitamins (B1, B2, B6, B12), amino acids, minerals, and growth-promoting factors that support cellular energy metabolism, protein synthesis, and follicle keratinocyte function. Packaged as EVs, these bioactive compounds are encapsulated in lipid bilayer vesicles that fuse with follicle cell membranes and deliver their cargo intracellularly with far greater efficiency than conventional ferment extracts. Galactomyces EVs support follicle metabolism, improve scalp microcirculation, and provide nutritional support to the dermal papilla cells that control the hair growth cycle.
• Biotinoyl Tripeptide-1 — a patented bioconjugate combining Biotin (Vitamin B7) with a tripeptide sequence (Gly-His-Lys, also known as GHK) that is specifically designed to address the follicle anchoring and growth mechanisms underlying hair thinning. The GHK tripeptide component has established activity in stimulating collagen and laminin synthesis in the perifollicular extracellular matrix, supporting the structural integrity of the follicle’s anchoring structures (the connective tissue sheath and dermal papilla). GHK also promotes the expression of adhesion molecules that anchor the follicle to the surrounding dermis, directly addressing the follicle loosening and miniaturization characteristic of androgenic alopecia. The Biotin component provides essential cofactor support for keratin synthesis in follicle keratinocytes. The conjugated form delivers both activities simultaneously to the follicle, making Biotinoyl Tripeptide-1 a more targeted and multifunctional active than either Biotin or the peptide alone.
• Phospholipids — the fundamental structural components of all cell membranes, composed of a glycerol backbone, two fatty acid chains, and a phosphate-linked head group. In the context of follicle-targeted scalp mesotherapy/microneedling, exogenous Phospholipids serve two roles: first, they replenish and reinforce the lipid bilayer integrity of follicle cell membranes and the perifollicular sebaceous structures, improving membrane fluidity, nutrient transport across the follicle cell membrane, and resistance to oxidative membrane damage; and second, they act as the structural vehicle for the extracellular vesicles in the formula — the EV membranes themselves are phospholipid bilayers, and additional free Phospholipids in the formula support EV stability, follicle uptake efficiency, and the overall lipid environment of the scalp dermis.

Treatment Area: Scalp & Hair
Recommended For: Androgenic alopecia, hair loss, thinning hair, scalp microbiome dysbiosis
Presentation: 5 x 10ml vials

What makes EXO-HAIR different from conventional hair loss mesotherapy? EXO-HAIR combines two distinct exosome technologies — Lactobacillus (postbiotic/microbiome-derived) and Galactomyces (ferment-derived) extracellular vesicles — with Biotinoyl Tripeptide-1 and Phospholipids in a single formula. Conventional hair mesotherapy delivers vitamins, minerals, and peptides as free molecules. EXO-HAIR delivers bioactive cargo packaged inside extracellular vesicles — lipid bilayer nano-capsules that fuse with follicle cell membranes and deliver their contents intracellularly, achieving a depth of cellular activation that free-molecule delivery cannot replicate. The addition of Lactobacillus EVs also uniquely addresses scalp microbiome dysbiosis — a hair loss driver that no conventional mesotherapy formula targets.

What is the scalp microbiome and how does it affect hair loss? The scalp microbiome is the community of microorganisms (bacteria, fungi, yeasts) that naturally colonize the scalp skin. A balanced microbiome supports a healthy scalp environment — regulating sebum, controlling inflammation, and maintaining follicle cycling. Dysbiosis (imbalance) — often characterized by overgrowth of Malassezia yeast or loss of protective Lactobacillus species — drives chronic perifollicular inflammation, disrupts the follicle immune privilege, and accelerates the miniaturization of follicles characteristic of androgenic and stress-related alopecia. Lactobacillus-derived EVs in EXO-HAIR address this root cause directly, delivering postbiotic anti-inflammatory signals that restore microbiome balance and reduce inflammation-driven hair loss.

What does Biotinoyl Tripeptide-1 do for hair loss that standard Biotin cannot? Standard Biotin supports keratin synthesis but does not address the follicle structural anchoring and miniaturization that drive androgenic alopecia. Biotinoyl Tripeptide-1 conjugates Biotin with the GHK tripeptide — which stimulates laminin and collagen synthesis in the perifollicular matrix and promotes adhesion molecule expression that anchors the follicle to the dermis. This dual action — keratin production support plus structural follicle anchoring — targets the root causes of hair thinning and follicle miniaturization more comprehensively than Biotin supplementation alone.

Who is this product for? SKINDERMA EXO-HAIR is formulated for licensed aesthetic practitioners, dermatologists, and trichologists performing professional exosome-based scalp mesotherapy and microneedling protocols for hair loss and androgenic alopecia. 

For professional use only. Not intended to diagnose, treat, cure, or prevent any disease.