{"title":"Microneedling","description":"\u003cp\u003e\u003cspan\u003eProfessional-grade microneedling mesotherapy serums, skin boosters, and exosome treatments formulated for advanced aesthetic results. Our curated selection supports collagen induction therapy, skin rejuvenation, and targeted dermal delivery, ideal for clinicians and skincare professionals seeking clinical-grade actives.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"skinderma-whitening-combo-5-x-10ml-vials","title":"SKINDERMA Whitening Combo 5 x 10ml Microneedling Mesotherapy Treatment","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Whitening Combo 5 x 10ml\u003c\/strong\u003e is a professional-grade brightening microneedling mesotherapy cocktail formulated to visibly reduce melanin synthesis and address pigmentation concerns. Its three active components work synergistically across the full melanogenesis cascade — inhibiting melanin production, intercepting oxidative intermediates, and accelerating the turnover of pigmented cells for a noticeably more radiant, even-toned complexion.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly reduces melanin synthesis and pigmentation at the enzymatic level\u003c\/li\u003e\n\u003cli\u003eInhibits tyrosinase — the key enzyme driving melanin overproduction\u003c\/li\u003e\n\u003cli\u003eEncourages gentle exfoliation of pigmented cells and promotes cellular renewal\u003c\/li\u003e\n\u003cli\u003eProtects against UV-induced and oxidative free radical damage\u003c\/li\u003e\n\u003cli\u003eImproves skin texture, smoothness, and radiance\u003c\/li\u003e\n\u003cli\u003eHelps diminish hyperpigmentation, dark spots, melasma, and photo-aging discoloration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlutathione\u003c\/strong\u003e — the body’s most potent endogenous antioxidant and one of the most extensively used skin-brightening actives in professional aesthetic medicine. Glutathione exerts its depigmenting effect through two complementary mechanisms. First, it directly inhibits tyrosinase — the copper-containing enzyme that catalyzes the conversion of tyrosine to DOPA and DOPA to dopaquinone, the rate-limiting steps in melanin biosynthesis — by binding to the copper ion in the enzyme’s active site, reducing its catalytic activity and suppressing melanin output. Second, Glutathione shifts the melanogenesis pathway from eumelanin (dark brown\/black pigment) production toward pheomelanin (lighter, yellow-red pigment) synthesis by interacting with dopaquinone intermediates and directing them toward cysteinyl-DOPA, the pheomelanin precursor. The cumulative effect of this dual mechanism is a progressive, visible lightening of hyperpigmented areas and an overall brightening of skin tone with continued professional treatment. Glutathione’s antioxidant activity simultaneously protects melanocytes from UV-induced oxidative stress — one of the primary triggers of reactive melanogenesis in melasma and photo-aging.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAscorbic Acid (Vitamin C)\u003c\/strong\u003e — a multifunctional depigmenting and antioxidant active with well-documented mechanisms across multiple steps of the melanogenesis cascade. Ascorbic Acid inhibits tyrosinase through copper chelation — binding to the copper ions in the enzyme’s active site and reducing its catalytic efficiency, complementing Glutathione’s tyrosinase inhibition through the same target but via a different binding mechanism. Additionally, Ascorbic Acid intercepts and reduces dopaquinone — the reactive melanin intermediate produced by tyrosinase — back to DOPA before it can polymerize into melanin, effectively short-circuiting the melanin production chain. As a potent antioxidant, Vitamin C also neutralizes reactive oxygen species (ROS) that stimulate melanocyte activity, and as a collagen synthesis cofactor (required for prolyl and lysyl hydroxylase activity), it supports dermal renewal and improves overall skin brightness and texture in treated areas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePyruvic Acid\u003c\/strong\u003e — an alpha-keto acid (the simplest member of the keto acid family) that exerts a controlled chemical exfoliation effect on the stratum corneum and upper epidermal layers. By disrupting corneocyte cohesion and accelerating desquamation, Pyruvic Acid promotes the shedding of melanin-loaded keratinocytes in the superficial epidermis — physically removing existing pigmentation while stimulating the proliferation of new, unpigmented keratinocytes from the basal layer. This accelerated cellular turnover amplifies the depigmenting effect of Glutathione and Vitamin C by clearing existing pigment from the skin surface while the other actives suppress new melanin production at the melanocyte level. Pyruvic Acid also has mild antimicrobial and sebum-regulating properties, making the formula additionally beneficial for post-acne pigmentation and oily skin types prone to dark spots.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Hyperpigmentation, dark spots, melasma, photo-aging, post-acne marks, uneven skin tone\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does SKINDERMA Whitening Combo reduce hyperpigmentation at the cellular level?\u003c\/strong\u003e Whitening Combo targets melanin overproduction through three simultaneous mechanisms: Glutathione and Ascorbic Acid both inhibit tyrosinase — the key enzyme in melanin biosynthesis — through complementary pathways (copper site binding and dopaquinone reduction respectively), while Glutathione simultaneously shifts melanogenesis toward lighter pheomelanin production. Pyruvic Acid then accelerates the turnover of pigmented cells in the upper epidermis, physically clearing existing melanin while the other actives suppress new production. At the professional concentrations used in mesotherapy protocols, this triple action reaches the melanocyte layer at therapeutic concentrations that topical brightening products cannot achieve.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is the difference between Glutathione and Vitamin C for skin brightening?\u003c\/strong\u003e Both inhibit tyrosinase but through different mechanisms that make them synergistic rather than redundant. Glutathione binds to the copper ion in tyrosinase’s active site and also shifts melanogenesis toward pheomelanin (lighter pigment). Ascorbic Acid chelates the same copper ion through a different binding chemistry and additionally reduces dopaquinone — the reactive melanin intermediate — back to DOPA before it can polymerize, intercepting the cascade at a later stage. Together they create a more complete blockade of the melanin production pathway than either active alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat types of pigmentation does this formula address?\u003c\/strong\u003e Whitening Combo is effective across all major pigmentation presentations: melasma (hormonally driven melanocyte hyperactivity), solar lentigines and photo-aging spots (UV-induced reactive melanogenesis), post-inflammatory hyperpigmentation (PIH) from acne, procedures, or trauma, and generalized uneven skin tone. Pyruvic Acid’s exfoliating action makes it particularly effective for surface-level pigmentation in the upper epidermis, while Glutathione and Vitamin C’s tyrosinase inhibition addresses melanin overproduction at the source.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Whitening Combo is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional brightening and depigmentation mesotherapy and microneedling protocols. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51749221925178,"sku":"SKD 1084","price":165.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/SKINDERMAWhiteningCombo5x10MLVIALS.jpg?v=1755518644"},{"product_id":"skinderma-exo-hair-5-x-10ml-vials","title":"SKINDERMA EXO-HAIR EXOSOME 5 x 10ml","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA EXO-HAIR 5 x 10ml\u003c\/strong\u003e is a remarkable advancement in aesthetic hair restoration, developed to address hair loss and promote exceptional hair rejuvenation through the next generation of exosome-based scalp mesotherapy\/microneedling. This professional-grade formula incorporates a unique synergy of \u003cstrong\u003eplant- and microbiome-derived extracellular vesicles\u003c\/strong\u003e and targeted bioactive ingredients, delivering regenerative signals directly to hair follicle cells to stimulate growth, strengthen roots, and restore scalp vitality.\u003c\/p\u003e\n\u003cp\u003eIdeal for aesthetic professionals performing scalp mesotherapy and microneedling hair restoration protocols for androgenic alopecia, diffuse hair loss, and hair thinning.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eStimulates hair follicle activity and promotes hair regrowth via exosome signaling\u003c\/li\u003e\n\u003cli\u003eAddresses androgenic alopecia and diffuse hair loss\u003c\/li\u003e\n\u003cli\u003eRestores scalp microbiome balance for a healthier follicle environment\u003c\/li\u003e\n\u003cli\u003eStrengthens hair roots and reduces shedding\u003c\/li\u003e\n\u003cli\u003eRevitalizes and nourishes the scalp at the cellular level\u003c\/li\u003e\n\u003cli\u003eSupports improved hair density and thickness over a course of treatments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactobacillus Extracellular Vesicles (Postbiotic Exosomes)\u003c\/strong\u003e — nano-sized extracellular vesicles derived from Lactobacillus probiotic bacteria, representing the cutting edge of postbiotic technology in scalp aesthetics. The scalp microbiome — the diverse ecosystem of bacteria, fungi, and other microorganisms that colonize the scalp skin — plays a critical and increasingly recognized role in follicle health. Dysbiosis (microbial imbalance) of the scalp microbiome is associated with chronic scalp inflammation, elevated Malassezia colonization, sebaceous gland disruption, and impaired follicle cycling — all of which contribute to hair loss progression. Lactobacillus-derived EVs carry postbiotic signaling molecules (including bacteriocins, short-chain fatty acids, and anti-inflammatory peptides) that modulate the scalp immune environment, reduce Th1\/Th17-driven perifollicular inflammation, support the restoration of a balanced microbiome, and create the optimal anti-inflammatory scalp environment for follicle regeneration. Unlike live probiotics, EVs are cell-free and stable, providing the beneficial signaling of Lactobacillus without the need for viable bacteria.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGalactomyces Extracellular Vesicles (Ferment-Derived Exosomes)\u003c\/strong\u003e — extracellular vesicles derived from Galactomyces ferment, a yeast-origin fermentation byproduct with a well-established track record in professional skin and scalp care. Galactomyces fermentation produces a rich cargo of vitamins (B1, B2, B6, B12), amino acids, minerals, and growth-promoting factors that support cellular energy metabolism, protein synthesis, and follicle keratinocyte function. Packaged as EVs, these bioactive compounds are encapsulated in lipid bilayer vesicles that fuse with follicle cell membranes and deliver their cargo intracellularly with far greater efficiency than conventional ferment extracts. Galactomyces EVs support follicle metabolism, improve scalp microcirculation, and provide nutritional support to the dermal papilla cells that control the hair growth cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiotinoyl Tripeptide-1\u003c\/strong\u003e — a patented bioconjugate combining Biotin (Vitamin B7) with a tripeptide sequence (Gly-His-Lys, also known as GHK) that is specifically designed to address the follicle anchoring and growth mechanisms underlying hair thinning. The GHK tripeptide component has established activity in stimulating collagen and laminin synthesis in the perifollicular extracellular matrix, supporting the structural integrity of the follicle’s anchoring structures (the connective tissue sheath and dermal papilla). GHK also promotes the expression of adhesion molecules that anchor the follicle to the surrounding dermis, directly addressing the follicle loosening and miniaturization characteristic of androgenic alopecia. The Biotin component provides essential cofactor support for keratin synthesis in follicle keratinocytes. The conjugated form delivers both activities simultaneously to the follicle, making Biotinoyl Tripeptide-1 a more targeted and multifunctional active than either Biotin or the peptide alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhospholipids\u003c\/strong\u003e — the fundamental structural components of all cell membranes, composed of a glycerol backbone, two fatty acid chains, and a phosphate-linked head group. In the context of follicle-targeted scalp mesotherapy\/microneedling, exogenous Phospholipids serve two roles: first, they replenish and reinforce the lipid bilayer integrity of follicle cell membranes and the perifollicular sebaceous structures, improving membrane fluidity, nutrient transport across the follicle cell membrane, and resistance to oxidative membrane damage; and second, they act as the structural vehicle for the extracellular vesicles in the formula — the EV membranes themselves are phospholipid bilayers, and additional free Phospholipids in the formula support EV stability, follicle uptake efficiency, and the overall lipid environment of the scalp dermis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Scalp \u0026amp; Hair\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Androgenic alopecia, hair loss, thinning hair, scalp microbiome dysbiosis\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat makes EXO-HAIR different from conventional hair loss mesotherapy?\u003c\/strong\u003e EXO-HAIR combines two distinct exosome technologies — Lactobacillus (postbiotic\/microbiome-derived) and Galactomyces (ferment-derived) extracellular vesicles — with Biotinoyl Tripeptide-1 and Phospholipids in a single formula. Conventional hair mesotherapy delivers vitamins, minerals, and peptides as free molecules. EXO-HAIR delivers bioactive cargo packaged inside extracellular vesicles — lipid bilayer nano-capsules that fuse with follicle cell membranes and deliver their contents intracellularly, achieving a depth of cellular activation that free-molecule delivery cannot replicate. The addition of Lactobacillus EVs also uniquely addresses scalp microbiome dysbiosis — a hair loss driver that no conventional mesotherapy formula targets.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is the scalp microbiome and how does it affect hair loss?\u003c\/strong\u003e The scalp microbiome is the community of microorganisms (bacteria, fungi, yeasts) that naturally colonize the scalp skin. A balanced microbiome supports a healthy scalp environment — regulating sebum, controlling inflammation, and maintaining follicle cycling. Dysbiosis (imbalance) — often characterized by overgrowth of Malassezia yeast or loss of protective Lactobacillus species — drives chronic perifollicular inflammation, disrupts the follicle immune privilege, and accelerates the miniaturization of follicles characteristic of androgenic and stress-related alopecia. Lactobacillus-derived EVs in EXO-HAIR address this root cause directly, delivering postbiotic anti-inflammatory signals that restore microbiome balance and reduce inflammation-driven hair loss.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does Biotinoyl Tripeptide-1 do for hair loss that standard Biotin cannot?\u003c\/strong\u003e Standard Biotin supports keratin synthesis but does not address the follicle structural anchoring and miniaturization that drive androgenic alopecia. Biotinoyl Tripeptide-1 conjugates Biotin with the GHK tripeptide — which stimulates laminin and collagen synthesis in the perifollicular matrix and promotes adhesion molecule expression that anchors the follicle to the dermis. This dual action — keratin production support plus structural follicle anchoring — targets the root causes of hair thinning and follicle miniaturization more comprehensively than Biotin supplementation alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA EXO-HAIR is formulated for licensed aesthetic practitioners, dermatologists, and trichologists performing professional exosome-based scalp mesotherapy and microneedling protocols for hair loss and androgenic alopecia. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51749251350842,"sku":"SKD 2005","price":173.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/SKINDERMAEXO-HAIR5x10ml.jpg?v=1755519459"},{"product_id":"epicexosome-20-billion-exosomes-advanced-skin-care","title":"EPICEXOSOME 20 Billion Bovine Milk Exosomes – Dual Exosome Technology Skin Rejuvenation Set","description":"\u003cp\u003e\u003cstrong\u003eEPICEXOSOME\u003c\/strong\u003e is the world’s first \u003cstrong\u003eDual Exosome Technology\u003c\/strong\u003e post-procedure system, uniquely combining \u003cstrong\u003eBovine Milk Exosomes\u003c\/strong\u003e and \u003cstrong\u003eCentella Asiatica (Asian Centella) Exosomes\u003c\/strong\u003e in a single advanced formula. Each vial contains over \u003cstrong\u003e20 billion lyophilized exosomes\u003c\/strong\u003e, freeze-dried to preserve their delicate bioactive structure and ensure maximum potency and stability.\u003c\/p\u003e\n\u003cp\u003eBlended with \u003cstrong\u003e4 encapsulated peptides\u003c\/strong\u003e, \u003cstrong\u003ePDRN\u003c\/strong\u003e, and \u003cstrong\u003e370+ skin-supporting proteins\u003c\/strong\u003e, EPICEXOSOME delivers next-generation cosmetic regeneration and recovery results for professional post-procedure skin care.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Cosmetic Benefits:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly improves skin elasticity and smoothness\u003c\/li\u003e\n\u003cli\u003eBrightens and evens skin tone\u003c\/li\u003e\n\u003cli\u003eDeeply hydrates and restores skin comfort\u003c\/li\u003e\n\u003cli\u003eReduces the appearance of redness and visible irritation\u003c\/li\u003e\n\u003cli\u003eSupports post-procedure skin recovery and regeneration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdvanced Dual Exosome Formula:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e20 Billion Bovine Milk Exosomes (validated by Nanoparticle Tracking Analysis)\u003c\/li\u003e\n\u003cli\u003eCentella Asiatica Exosomes\u003c\/li\u003e\n\u003cli\u003ePDRN (Polydeoxyribonucleotide) | Hyaluronate | Stem Cell Extracts\u003c\/li\u003e\n\u003cli\u003e4 Encapsulated Peptides | 370+ Bioactive Proteins\u003c\/li\u003e\n\u003cli\u003eLyophilized (freeze-dried) for maximum preservation and potency\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIdeal for professional post-treatment protocols including \u003cstrong\u003emicroneedling, lasers, RF needling,\u003c\/strong\u003e and \u003cstrong\u003echemical peels\u003c\/strong\u003e. Formulated for aesthetic professionals seeking science-driven skin regeneration results.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 1 Set EpicExosome\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy Bovine Milk Exosomes?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eExosomes are nano-sized extracellular vesicles (30–150nm) secreted by cells to carry growth factors, microRNA, signaling proteins, and bioactive lipids between cells, functioning as the body’s intercellular communication system. Bovine Milk Exosomes are among the most biocompatible and biomimetically relevant exosome sources for human skin application: milk-derived exosomes are naturally abundant, scalable, and highly stable, and their surface protein profiles closely mirror those of human cell-derived exosomes, allowing them to be recognized and internalized by human skin cells with high efficiency. Bovine Milk Exosomes carry a rich natural cargo of growth factors, microRNA sequences, anti-inflammatory proteins, and regenerative signaling molecules that activate skin cell repair, collagen synthesis, and inflammation resolution, making them particularly effective for post-procedure recovery where the skin’s own regenerative signaling is overwhelmed. Each vial’s 20 billion exosome count is validated by Nanoparticle Tracking Analysis (NTA), the gold standard method for measuring exosome concentration and particle size distribution.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy the Dual Exosome Approach?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEPICEXOSOME’s proprietary combination pairs Bovine Milk Exosomes (delivering growth factor and regenerative protein cargo) with Centella Asiatica Exosomes, plant-derived nano-vesicles carrying the concentrated bioactive triterpenoids of Centella (asiaticoside, madecassoside) in an exosome delivery format that dramatically enhances their cellular uptake compared to conventional botanical extract. The two exosome populations act synergistically: Bovine Milk Exosomes activate fibroblast regeneration and anti-inflammatory pathways, while Centella Exosomes deliver collagen-stimulating triterpenoids with enhanced dermal penetration. Together they address post-procedure recovery, collagen rebuilding, and inflammation resolution simultaneously.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is PDRN and why is it in this formula?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePDRN supports tissue comfort and skin renewal at a cellular level.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 1. Reconstitute:\u003c\/strong\u003e Open the vials. Pour the Centella Asiatica Exosome with PDRN Serum (solvent) into the lyophilized Bovine Milk Exosome vial. Gently swirl until fully dissolved. Do not shake.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 2. Cleanse \u0026amp; Prepare:\u003c\/strong\u003e Ensure the skin is clean and dry. If used post-procedure (after microneedling or laser), proceed immediately after while the skin is most receptive.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 3. Apply:\u003c\/strong\u003e Dispense the reconstituted serum with a sterile syringe. Apply evenly across the face and neck using gentle pressing motions. Avoid rubbing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 4. Absorb:\u003c\/strong\u003e Allow the serum to fully absorb. Do not rinse. Follow with your practice treatment protocol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 5. Frequency:\u003c\/strong\u003e Use as a standalone treatment or as part of your post-procedure recovery routine. One set per session is recommended. Optimal results develop with consistent use over 4–6 weeks.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e For full scientific details, visit the official EPICEXOSOME site: \u003ca href=\"https:\/\/epicexosome.com\"\u003ehttps:\/\/epicexosome.com\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e🍁 Proudly Canadian brand | Made in EU\u003c\/p\u003e","brand":"EPICEXOSOME","offers":[{"title":"Default Title","offer_id":51795112132922,"sku":"EpicExo-1-Set","price":140.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/EPICEXOSOME20BillionExosomesAdvancedSkinCare-1.jpg?v=1755520959"},{"product_id":"skinderma-hair-booster-5-x-10ml-vials","title":"SKINDERMA Hair Booster 5 x 10ml vials","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Hair Booster 5 x 10ml\u003c\/strong\u003e is a professional scalp mesotherapy cocktail formulated to increase the vascularization of hair follicles through direct vasodilatory action, prolong the anagen (growth) phase of the hair cycle, and provide the nutritional and antioxidant support essential for healthy follicle metabolism. Suitable for both men and women experiencing hair loss or androgenetic alopecia.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eIncreases follicle vascularization and scalp microcirculation through direct vasodilatory action\u003c\/li\u003e\n\u003cli\u003eProlongs the anagen (active growth) phase of the hair cycle\u003c\/li\u003e\n\u003cli\u003eSupports keratin production and hair shaft protein synthesis\u003c\/li\u003e\n\u003cli\u003eProvides antioxidant protection against oxidative stress-driven follicle damage\u003c\/li\u003e\n\u003cli\u003eReinforces scalp connective tissue and follicle anchoring structures\u003c\/li\u003e\n\u003cli\u003eSuitable for androgenetic alopecia in both men and women\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePanthenol (Provitamin B5)\u003c\/strong\u003e — a precursor to Coenzyme A that supports keratinocyte proliferation, cellular energy metabolism, and the synthesis of structural proteins in the hair shaft. Panthenol also improves scalp barrier function and reduces inflammation, creating a healthier environment for follicle activity. Its humectant properties help maintain optimal scalp hydration, which is essential for follicle metabolism and cycling.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiotin (Vitamin B7)\u003c\/strong\u003e — an essential cofactor for carboxylase enzymes involved in fatty acid synthesis and amino acid metabolism, and a direct driver of keratin production in hair follicle keratinocytes. Biotin deficiency is directly associated with hair thinning, increased shedding, and impaired follicle cycling. In scalp mesotherapy protocols, Biotin reaches follicle keratinocytes at therapeutic concentrations that oral supplementation cannot guarantee due to absorption variability — directly supporting hair shaft protein synthesis and follicle metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylsilanol Mannuronate (Organic Silicium)\u003c\/strong\u003e — a bioavailable marine-derived form of silicon that strengthens the connective tissue structures surrounding hair follicles, stimulates fibroblast activity in the perifollicular dermis, and reinforces collagen and elastin cross-linking. Silicon is a structural component of the hair shaft itself, and adequate dermal silicon availability is associated with improved hair strength, reduced breakage, and better anchoring of the follicle within the dermal papilla.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHydrolyzed Collagen\u003c\/strong\u003e — low-molecular-weight collagen peptides that are readily absorbed by dermal fibroblasts and follicle-associated connective tissue. These peptides provide a direct supply of proline, glycine, and hydroxyproline — the primary amino acids required for collagen synthesis in the perifollicular dermal sheath. Hydrolyzed Collagen also stimulates fibroblast activity and supports the structural integrity of the dermal papilla, which is critical for maintaining follicle health and anchoring during the hair growth cycle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlutathione\u003c\/strong\u003e — the body’s most potent endogenous antioxidant, composed of glutamate, cysteine, and glycine. In hair loss biology, oxidative stress is a key driver of premature follicle miniaturization, inflammation of the perifollicular tissue, and accelerated transition from the anagen (growth) to catagen (regression) phase. Glutathione neutralizes reactive oxygen species (ROS) in the scalp dermis, reduces oxidative damage to follicle stem cells and the dermal papilla, and helps maintain the antioxidant capacity of the follicular microenvironment — supporting longer anagen duration and healthier follicle cycling. Glutathione also inhibits the enzyme tyrosinase, which has a secondary brightening effect on the scalp skin.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Scalp\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Hair loss, androgenetic alopecia (men and women)\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does SKINDERMA Hair Booster stimulate hair growth?\u003c\/strong\u003e Hair Booster works through four complementary mechanisms: it increases follicle vascularization via direct vasodilatory action, delivering more oxygen and nutrients to follicle cells; Biotin and Panthenol support keratin synthesis and follicle keratinocyte metabolism; Organic Silicium and Hydrolyzed Collagen reinforce the perifollicular connective tissue and dermal papilla; and Glutathione neutralizes oxidative stress that drives premature follicle miniaturization and catagen transition — collectively prolonging the anagen phase and improving hair density over a course of treatments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat role does oxidative stress play in hair loss and how does Glutathione help?\u003c\/strong\u003e Oxidative stress — caused by an excess of reactive oxygen species (ROS) relative to the scalp’s antioxidant defenses — is a significant contributor to androgenetic alopecia and diffuse hair loss. ROS damage follicle stem cells, inflame the perifollicular dermis, and accelerate the transition from the anagen (growth) to catagen (regression) phase, shortening the growth cycle and reducing hair density over time. Glutathione — the body’s primary endogenous antioxidant — neutralizes ROS in the scalp dermis, protecting follicle stem cells and supporting longer, healthier anagen cycles.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is professional scalp mesotherapy more effective than topical hair loss treatments?\u003c\/strong\u003e Topical hair loss treatments (shampoos, serums, lotions) face a significant barrier in the scalp’s skin — most actives cannot penetrate to the depth of the hair follicle bulb and dermal papilla in clinically meaningful concentrations. Scalp mesotherapy places Biotin, Panthenol, Glutathione, Silicium, and Collagen peptides directly in the dermis adjacent to the follicle bulb, ensuring therapeutic concentrations reach the target tissue and providing a more direct and potent stimulus for follicle activity than topical application can achieve.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Hair Booster is formulated for licensed aesthetic practitioners, dermatologists, and trichologists performing professional scalp mesotherapy protocols for hair loss and androgenetic alopecia in both male and female. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51752692252986,"sku":"SKD 1082","price":100.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/hairbooster.jpg?v=1755592267"},{"product_id":"skinderma-antiaging-combo-5-x-10ml-vials","title":"SKINDERMA Antiaging Combo – Multi-Active Collagen \u0026 Wrinkle Mesotherapy Cocktail 5 x 10ml","description":"\u003cp\u003eSKINDERMA Antiaging Combo is a comprehensive professional microneedling mesotherapy cocktail combining five powerful actives to promote collagen production, minimize wrinkles, deeply moisturize, firm the skin, and inhibit facial muscle contractions — delivering a complete multi-pathway anti-aging treatment in a single protocol. Each ingredient targets a distinct mechanism of skin aging, and together they address the full spectrum of facial aging concerns simultaneously.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePromotes collagen production and deep skin rejuvenation\u003c\/li\u003e\n\u003cli\u003eMinimizes fine lines, wrinkles, and expression lines\u003c\/li\u003e\n\u003cli\u003eDeeply moisturizes and restores skin volume and plumpness\u003c\/li\u003e\n\u003cli\u003eFirms and lifts sagging skin on face and neck\u003c\/li\u003e\n\u003cli\u003eInhibits facial muscle contractions to prevent new expression lines\u003c\/li\u003e\n\u003cli\u003eAntioxidant and barrier-repair protection for long-term skin health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePanthenol (Provitamin B5)\u003c\/strong\u003e — the alcohol analog of pantothenic acid (Vitamin B5) and a direct precursor to Coenzyme A, which is essential for fatty acid synthesis and cellular energy metabolism. In skin biology, Panthenol is a highly effective humectant that attracts and retains moisture in the dermis, and a proven wound-healing and barrier-repair active — stimulating keratinocyte proliferation, accelerating epidermal repair, and supporting fibroblast differentiation and collagen synthesis. In mesotherapy protocols, Panthenol enhances the skin’s structural repair capacity and contributes to the formula’s overall anti-aging and skin renewal effect.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDMAE (Dimethylaminoethanol)\u003c\/strong\u003e — a naturally occurring choline precursor that increases acetylcholine availability in the dermis, enhancing the tone of underlying facial musculature for a visible lifting and firming effect on lax skin. DMAE also stabilizes cell membrane phospholipid bilayers, increasing membrane rigidity and protecting against oxidative damage — contributing both a mechanical firming action and antioxidant protection to the formula.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrganic Silicium (Methylsilanol Mannuronate)\u003c\/strong\u003e — a bioavailable marine-derived form of silicon that plays a structural role in the extracellular matrix by stimulating fibroblast activity and reinforcing collagen and elastin cross-linking. Silicium is a cofactor in the hydroxylation of proline and lysine residues in collagen — the key step in forming stable, cross-linked collagen fibrils. As the skin’s Silicium content declines with age, supplementation via mesotherapy directly supports the structural renewal of the dermis, improving skin density, firmness, and elasticity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAsian Centella (Centella asiatica Extract)\u003c\/strong\u003e — standardized for its four active triterpenoids (asiaticoside, madecassoside, asiatic acid, madecassic acid), which collectively stimulate fibroblast proliferation and collagen type I and III synthesis, inhibit collagenase-mediated matrix degradation, strengthen capillary walls, and reduce inflammation. Centella provides the formula’s primary collagen-stimulating and microvascular support action, complementing the structural reinforcement provided by Silicium.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate\u003c\/strong\u003e — the sodium salt of hyaluronic acid, with an extraordinary capacity to bind up to 1,000 times its weight in water. In mesotherapy protocols, it restores deep dermal hydration, replenishes lost skin volume, and creates the optimal hydrated environment for fibroblast activity and collagen synthesis — amplifying the regenerative effect of the formula’s other actives while providing immediate visible plumping and wrinkle-filling results.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Expression lines, eye contour, sagging skin, fine lines, and wrinkles\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat makes SKINDERMA Antiaging Combo a complete anti-aging protocol in one vial?\u003c\/strong\u003e Antiaging Combo targets five distinct mechanisms of skin aging simultaneously: Sodium Hyaluronate restores dermal hydration and volume; DMAE lifts and firms via acetylcholine-mediated muscle tone and membrane stabilization; Organic Silicium reinforces collagen and elastin cross-linking; Centella asiatica stimulates fibroblast collagen synthesis and microvascular integrity; and Panthenol supports epidermal repair and barrier function. Together, they address hydration loss, structural laxity, muscle-driven expression lines, collagen depletion, and barrier impairment — the five primary drivers of visible facial aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Organic Silicium contribute to collagen formation?\u003c\/strong\u003e Silicon is a structural cofactor in collagen biosynthesis — specifically in the hydroxylation of proline and lysine residues, which is required to form stable cross-linked collagen fibrils. Skin Silicium content declines significantly with age, contributing to reduced collagen density and skin laxity. Methylsilanol Mannuronate (Organic Silicium) delivers bioavailable silicon directly to the dermis via mesotherapy, supporting the enzymatic steps in collagen fiber formation and the cross-linking of elastin — improving skin density, firmness, and structural resilience over a course of treatments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does Antiaging Combo address?\u003c\/strong\u003e This formula is recommended for mature skin with multiple concurrent aging concerns — including fine lines and deep wrinkles, sagging and lax skin, loss of volume and hydration, dull complexion, expression lines, and impaired skin barrier function. Its multi-pathway approach makes it ideal as a comprehensive rejuvenation protocol or as a foundational treatment combined with targeted actives for specific concerns.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Antiaging Combo is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional multi-active anti-aging mesotherapy and microneedling protocols. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51752890433850,"sku":"SKD 1077","price":121.63,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/antiagingcombo.jpg?v=1755596591"},{"product_id":"skinderma-argireline-20-x-2ml","title":"SKINDERMA Argireline Ampoules – Neuro-Relaxing Peptide Anti-Wrinkle Microneedling Mesotherapy 20 x 2ml","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Argireline 20 x 2ml\u003c\/strong\u003e is a professional mesotherapy solution featuring \u003cstrong\u003eArgireline (Acetyl Hexapeptide-3)\u003c\/strong\u003e and \u003cstrong\u003eLeuphasil (Pentapeptide-18)\u003c\/strong\u003e — two complementary neuro-relaxing peptides that work through distinct but synergistic mechanisms to visibly soften expression lines and prevent new wrinkles from forming. This dual-peptide formula delivers one of the most comprehensive neuromodulating protocols available to aesthetic practitioners.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly reduces expression lines and dynamic wrinkles\u003c\/li\u003e\n\u003cli\u003eDual neuro-relaxing peptide action via two independent pathways\u003c\/li\u003e\n\u003cli\u003ePrevents formation of new expression lines\u003c\/li\u003e\n\u003cli\u003eSmooths and refines skin texture on face and neck\u003c\/li\u003e\n\u003cli\u003eNon-invasive alternative to neurotoxin wrinkle treatments\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eArgireline — Acetyl Hexapeptide-3 (Acetyl Hexapeptide-8)\u003c\/strong\u003e — the most extensively researched neuromodulating peptide in aesthetic medicine. Argireline is a synthetic hexapeptide that structurally mimics the N-terminal domain of SNAP-25, one of the three proteins that form the SNARE complex — the molecular machine responsible for docking and fusing acetylcholine-containing vesicles with the presynaptic membrane of motor neurons. By competitively binding to the SNARE complex assembly site, Argireline prevents the complete formation of the SNARE complex, inhibiting the calcium-triggered exocytosis of acetylcholine vesicles. The result is a dose-dependent reduction in acetylcholine release at the neuromuscular junction — reducing the frequency and intensity of repetitive facial muscle contractions (such as squinting, frowning, and smiling) that create and deepen expression lines over time. Unlike neuromodulator treatments that irreversibly cleave and permanently inactivate SNAP-25, Argireline acts competitively and reversibly — allowing safe, repeated use in mesotherapy protocols with no risk of permanent muscle paralysis. The wrinkle-softening effect builds progressively over a course of treatments and is particularly pronounced in the forehead, glabellar (frown), periocular (crow’s feet), and perioral regions.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLeuphasil — Pentapeptide-18\u003c\/strong\u003e — a synthetic enkephalin analog (a class of endogenous opioid peptides) that acts through a completely different neuromodulatory pathway from Argireline. Leuphasil binds to opioid receptors at the presynaptic membrane, activating G-protein coupled inhibitory signaling (Gi\/Go) that reduces intracellular cAMP levels and inhibits voltage-gated calcium channels. The net effect is a reduction in calcium influx into the motor neuron terminal — independently decreasing acetylcholine vesicle exocytosis through the opioid receptor pathway rather than SNARE complex competition. This dual-pathway approach — Argireline targeting SNARE assembly, Leuphasil targeting calcium channel-mediated vesicle release — produces a synergistic inhibition of neuromuscular transmission that is greater than either peptide alone, making the combination formula significantly more effective for expression line reduction than single-peptide protocols.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Expression lines, dynamic wrinkles, anti-aging neuro-relaxing peptide protocols\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 2ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Argireline and how does it reduce expression lines?\u003c\/strong\u003e Argireline (Acetyl Hexapeptide-3) mimics the N-terminal domain of SNAP-25 — a key protein in the SNARE complex that controls acetylcholine release at the neuromuscular junction. By competitively binding to the SNARE complex, Argireline inhibits the vesicle fusion that releases acetylcholine, reducing the muscle contraction signals that create and deepen expression lines. The effect is reversible and builds progressively over mesotherapy sessions — making it a safe, non-invasive alternative for practitioners and patients seeking needle-free neuromodulation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Leuphasil and how does it differ from Argireline?\u003c\/strong\u003e Leuphasil (Pentapeptide-18) is a synthetic enkephalin analog that acts on opioid receptors at the presynaptic motor neuron membrane, activating inhibitory G-protein signaling (Gi\/Go) that reduces intracellular cAMP and inhibits voltage-gated calcium channels — independently decreasing calcium-triggered acetylcholine release. While Argireline blocks SNARE complex assembly downstream of calcium influx, Leuphasil reduces calcium influx itself — the two peptides act on different points in the neurotransmission cascade, producing a synergistic inhibitory effect on muscle contraction that exceeds what either peptide achieves alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does the dual-peptide formula compare to single neuromodulating peptide protocols?\u003c\/strong\u003e Single-peptide protocols target only one point in the neurotransmission pathway. SKINDERMA Argireline’s dual formula targets two independent mechanisms simultaneously — Argireline at the SNARE complex level and Leuphasil at the calcium channel level — producing a synergistic reduction in acetylcholine release that is greater than either peptide alone. This makes the combination protocol more effective for progressive expression line reduction across a course of mesotherapy sessions.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Argireline is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional anti-wrinkle and neuro-relaxing peptide mesotherapy and microneedling protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51752992178490,"sku":"SKD 1038","price":88.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/argireline.jpg?v=1755597366"},{"product_id":"skinderma-asian-centella-ampoules-20-x-5ml","title":"SKINDERMA Asian Centella 20 x 5ml – Circulation \u0026 Skin Rejuvenation Microneedling Mesotherapy","description":"\u003ch2\u003eSKINDERMA Asian Centella Ampoules, 20 x 5ml\u003c\/h2\u003e\n\u003cp\u003eSKINDERMA Asian Centella is a professional microneedling and mesotherapy solution with Centella asiatica. It improves blood circulation, especially in areas affected by cellulite, strengthens the skin and stimulates connective tissue. It helps strengthen capillaries and veins and contributes to better blood circulation.\u003c\/p\u003e\n\u003ch3\u003eKey Benefits\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eAccelerates cell regeneration and increases collagen production\u003c\/li\u003e\n\u003cli\u003eImproves blood circulation in the skin\u003c\/li\u003e\n\u003cli\u003eReduces the appearance of fine lines and wrinkles\u003c\/li\u003e\n\u003cli\u003eHydrates and moisturizes the skin\u003c\/li\u003e\n\u003cli\u003eMinimizes the appearance of pores\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Cellulite, wrinkles, stretch marks, acne scars, hair loss, skin rejuvenation.\u003cbr\u003e\n\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Asian Centella Extract 1%.\u003cbr\u003e\n\u003cstrong\u003eApplication:\u003c\/strong\u003e Microneedling and mesotherapy for face, neck and hair. Mesotherapy for body cellulite protocols.\u003cbr\u003e\n\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face, neck and hair, plus body cellulite protocols.\u003cbr\u003e\n\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules.\u003cbr\u003e\n\u003cstrong\u003eBrand:\u003c\/strong\u003e SKINDERMA, made in Spain.\u003c\/p\u003e\n\u003cp\u003eFor licensed aesthetic professionals.\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753040118074,"sku":"SKD 1039","price":78.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/asiancentella.jpg?v=1755598416"},{"product_id":"skinderma-biotin-ampoules-20-x-2ml","title":"SKINDERMA Biotin ampoules 20 x 2ml","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Biotin ampoules 20 x 2ml\u003c\/strong\u003e deliver a targeted dose of \u003cstrong\u003eBiotin (Vitamin H \/ Vitamin B7)\u003c\/strong\u003e directly into the skin and scalp, supporting cell repair, barrier function, and healthy tissue growth. This dual-purpose professional ampoule is ideal for both skin and hair microneedling mesotherapy protocols, addressing sebum regulation, dry skin conditions, and hair loss in one versatile formula.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eStimulates cell repair and improves skin structure and appearance\u003c\/li\u003e\n\u003cli\u003eStrengthens the skin’s natural barrier by accelerating lipid production\u003c\/li\u003e\n\u003cli\u003eDelivers a visible anti-wrinkle effect\u003c\/li\u003e\n\u003cli\u003eRegulates sebum secretion for oily and combination skin\u003c\/li\u003e\n\u003cli\u003eHelps relieve symptoms of dry skin, eczema, and seborrhoeic dermatitis\u003c\/li\u003e\n\u003cli\u003eSupports healthy hair growth and acts against hair loss\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiotin (Vitamin H \/ Vitamin B7)\u003c\/strong\u003e — an essential water-soluble B-vitamin that serves as a critical cofactor for carboxylase enzymes involved in fatty acid synthesis, amino acid metabolism, and gluconeogenesis. In skin and hair biology, Biotin’s role is multifaceted and clinically significant across several pathways: \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eKeratin synthesis:\u003c\/strong\u003e Biotin is essential for the production of keratin — the structural protein that forms the hair shaft, nail plate, and the outermost layers of the epidermis. Biotin deficiency is directly associated with brittle, thinning hair, nail fragility, and impaired epidermal integrity. At the follicle and keratinocyte level, Biotin replenishes cellular reserves that oral supplementation cannot reliably match due to gastrointestinal absorption variability. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eLipid synthesis and skin barrier function:\u003c\/strong\u003e As a cofactor for acetyl-CoA carboxylase, Biotin is required for the synthesis of long-chain fatty acids — the building blocks of the skin’s lipid barrier (ceramides, free fatty acids, cholesterol). Biotin accelerates lipid production in keratinocytes, reinforcing the stratum corneum barrier, reducing transepidermal water loss (TEWL), and improving the skin’s resistance to irritants and allergens — making it effective for dry skin, eczema, and seborrhoeic dermatitis. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eSebum regulation:\u003c\/strong\u003e Biotin modulates sebaceous gland activity, helping to normalize sebum secretion in oily and combination skin types. This makes it uniquely versatile — improving barrier function in dry\/sensitive skin while simultaneously reducing excess oiliness in seborrhoeic conditions. \u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eHair follicle support:\u003c\/strong\u003e At the scalp level, Biotin supports follicle keratinocyte metabolism, hair shaft protein synthesis, and follicle cycling, contributing to improved hair density, reduced shedding, and healthier hair growth over a course of treatments.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Skin \u0026amp; Scalp\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Sebum regulation, oily skin, dry skin, eczema, seborrhoeic dermatitis, hair loss, healthy skin cell growth\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 2ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat does Biotin do for skin and hair in microneedling and mesotherapy protocols?\u003c\/strong\u003e Biotin is an essential cofactor for carboxylase enzymes involved in keratin synthesis, fatty acid production, and amino acid metabolism. At the follicle and keratinocyte level, it supports hair shaft protein synthesis, reinforces the skin’s lipid barrier, and normalizes sebum production — addressing hair loss, barrier impairment, and sebaceous dysregulation in a single active.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is Biotin microneedling and mesotherapy more effective than oral Biotin supplements for hair loss?\u003c\/strong\u003e Oral Biotin must be absorbed through the gastrointestinal tract, distributed systemically, and then reach the scalp follicles — a process subject to absorption variability, competition with other nutrients, and systemic dilution. Mesotherapy places Biotin directly in the dermis adjacent to hair follicles, maximizing local concentration at the site of action and providing a more immediate and targeted stimulus for follicle keratinocyte metabolism.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin conditions is Biotin microneedling and mesotherapy recommended for?\u003c\/strong\u003e SKINDERMA Biotin is recommended for dry, dehydrated skin with impaired barrier function, eczema and seborrhoeic dermatitis, oily and combination skin requiring sebum regulation, aging skin requiring cell renewal support, and hair thinning or loss requiring follicle-level nutritional support. Its versatility across both skin and scalp protocols makes it one of the most multi-functional vitamin actives in mesotherapy and microneedling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Biotin is formulated for licensed aesthetic practitioners, dermatologists, trichologists, and skin clinics performing professional skin and scalp microneedling and mesotherapy protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753053716794,"sku":"SKD 1040","price":81.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/biotin.jpg?v=1755598846"},{"product_id":"skinderma-btx-complex-5-x-10ml-vials","title":"SKINDERMA BTX Complex – Peptide Lifting \u0026 Wrinkle Microneedling Mesotherapy","description":"\u003cp\u003eSKINDERMA BTX Complex is a professional microneedling mesotherapy solution powered by neuro-relaxing peptides that mimic the effect of Botulinum Toxin — lifting the skin, reducing expression lines, and regenerating collagen fibres for visibly firmer, smoother skin. Unlike neuromodulators, BTX Complex delivers its wrinkle-relaxing and lifting effect non-invasively via mesotherapy protocol.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly lifts and firms sagging skin on face and neck\u003c\/li\u003e\n\u003cli\u003eReduces medium and deep wrinkles and expression lines\u003c\/li\u003e\n\u003cli\u003ePromotes collagen fibre regeneration for increased skin density and tension\u003c\/li\u003e\n\u003cli\u003eRelaxes facial muscle contractions for a smoother appearance\u003c\/li\u003e\n\u003cli\u003eEffective non-invasive alternative for wrinkle treatment protocols\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcetyl Hexapeptide-8 (Argireline)\u003c\/strong\u003e — one of the most extensively researched neuromodulating peptides in aesthetic medicine. Argireline is a hexapeptide analog of the N-terminal end of SNAP-25, a key protein in the SNARE complex responsible for vesicle docking and neurotransmitter release at the neuromuscular junction. By competing with SNAP-25 for the SNARE complex assembly, Argireline inhibits the calcium-dependent exocytosis of acetylcholine vesicles from motor neuron terminals, reducing the signal that triggers muscle contraction. This produces a localized, reversible muscle-relaxing effect that softens repetitive expression lines and dynamic wrinkles — particularly in the forehead, periocular (crow’s feet), and perioral regions. Unlike Botulinum Toxin, which irreversibly cleaves SNARE proteins, Argireline acts competitively and reversibly, making it safe for repeated use in mesotherapy protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcetyl Hexapeptide-30\u003c\/strong\u003e — a complementary neuromodulating peptide that targets the presynaptic release of catecholamines (noradrenaline and adrenaline) at adrenergic nerve terminals in addition to its effect on the SNARE complex. This dual neuromodulatory action extends the wrinkle-relaxing effect beyond the cholinergic pathway, addressing a broader range of muscle contraction signals and enhancing the overall anti-expression line efficacy of the formula.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDimethyl MEA (Dimethylethanolamine)\u003c\/strong\u003e — a precursor to choline and phosphatidylcholine that incorporates into cell membrane phospholipid bilayers, increasing membrane rigidity and reducing fluidity. This membrane-stabilizing action produces a tightening and lifting effect on skin cells, improving skin tone and firmness. Dimethyl MEA also supports acetylcholine synthesis as a choline precursor, and has antioxidant properties that protect skin cells from free radical damage.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Sagging skin, medium\/deep wrinkles, expression lines, and damaged skin\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Argireline and how does it reduce wrinkles?\u003c\/strong\u003e Argireline (Acetyl Hexapeptide-8) is a peptide that mimics part of the SNAP-25 protein in the SNARE complex — the molecular machinery responsible for releasing acetylcholine at the neuromuscular junction. By competing with SNAP-25 for SNARE complex assembly, Argireline inhibits the acetylcholine release that triggers muscle contraction, producing a reversible muscle-relaxing effect that softens expression lines. Delivered via microneedling and mesotherapy, it achieves a clinically meaningful neuromodulating effect.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does BTX Complex compare to Botulinum Toxin (Botox)?\u003c\/strong\u003e Botulinum Toxin works by irreversibly cleaving SNARE proteins (specifically SNAP-25), preventing acetylcholine release and paralyzing the target muscle for 3–6 months. BTX Complex peptides act competitively and reversibly — blocking SNARE assembly without destroying the proteins. The effect is more gradual and moderate than Botox, building progressively over a course of mesotherapy sessions. BTX Complex is suitable for patients seeking a non-invasive alternative or maintenance between Botox treatments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat expression lines and wrinkles does BTX Complex treat?\u003c\/strong\u003e BTX Complex is most effective for dynamic wrinkles caused by repetitive facial muscle contractions — including forehead lines, frown lines (glabellar), crow’s feet (periocular), perioral lines, and neck bands. It also improves overall skin firmness and elasticity through the membrane-stabilizing action of Dimethyl MEA, making it suitable as a comprehensive anti-aging and lifting mesotherapy protocol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA BTX Complex is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional anti-aging, lifting, and wrinkle-reduction microneedling and mesotherapy protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753081635130,"sku":"SKD 1078","price":159.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/btxcomplex.jpg?v=1755599283"},{"product_id":"skinderma-caffeine-10-ampoules-20-x-1ml","title":"SKINDERMA Caffeine 10% ampoules 20 x 1ml","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Caffeine 10% ampoules 20 x 1ml\u003c\/strong\u003e deliver a targeted dose of high-concentration caffeine directly into the skin to accelerate blood flow, stimulate fat release from adipocytes, and visibly minimize the appearance of cellulite. This professional-grade microneedling mesotherapy ampoule is ideal for body remodeling and localized weight reduction protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAccelerates blood flow and microcirculation in treated areas\u003c\/li\u003e\n\u003cli\u003eStimulates the release of stored fats from adipocytes into the metabolism\u003c\/li\u003e\n\u003cli\u003eVisibly minimizes the appearance of cellulite\u003c\/li\u003e\n\u003cli\u003eSupports localized body remodeling and weight reduction\u003c\/li\u003e\n\u003cli\u003eTones and firms skin in treated areas\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaffeine (10%)\u003c\/strong\u003e — a methylxanthine compound that exerts its lipolytic effect primarily through inhibition of phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic adenosine monophosphate (cAMP) inside adipocytes. By inhibiting PDE, Caffeine causes intracellular cAMP levels to rise, which activates protein kinase A (PKA) and in turn activates hormone-sensitive lipase (HSL) — the key enzyme that hydrolyzes triglycerides stored within fat cells into free fatty acids and glycerol. These are then released from the adipocyte and transported via the bloodstream for metabolic clearance. In parallel, Caffeine stimulates local microcirculation by promoting vasodilation and improving vascular tone, which enhances lymphatic drainage and reduces the fluid accumulation contributing to oedematous cellulite. At 10% professional concentration, Caffeine achieves a lipolytic stimulus in targeted adipose tissue that topical caffeine formulations cannot replicate, making it one of the most clinically effective anti-cellulite actives available to aesthetic practitioners.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Cellulite, body remodeling, localized fat reduction\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 1ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Caffeine mesotherapy reduce cellulite?\u003c\/strong\u003e Caffeine inhibits phosphodiesterase (PDE), causing intracellular cAMP to accumulate in adipocytes. Elevated cAMP activates hormone-sensitive lipase (HSL), which hydrolyzes stored triglycerides into free fatty acids and glycerol for metabolic clearance. Caffeine also improves local microcirculation and lymphatic drainage — reducing the fluid retention and vascular stasis that contribute to oedematous cellulite. At 10% professional concentration, it achieves a lipolytic stimulus in targeted tissue that topical caffeine products cannot replicate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is professional-grade Caffeine mesotherapy more effective than topical anti-cellulite creams?\u003c\/strong\u003e Topical caffeine formulations face a significant absorption barrier — the stratum corneum limits penetration, and only a fraction of the applied dose reaches the adipose tissue beneath. At 10% concentration delivered via mesotherapy protocol, Caffeine reaches adipocytes at a therapeutically active concentration, directly triggering the cAMP-HSL lipolysis cascade and microcirculatory improvements that topical application cannot achieve at meaningful depth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat protocols combine well with Caffeine mesotherapy?\u003c\/strong\u003e Caffeine is frequently combined with L-Carnitine (to accelerate the metabolic clearance of released fatty acids), Phosphatidylcholine or Lipase (for direct adipocytolysis), Hyaluronidase (as a diffusion enhancer), and Organic Silicium (for skin firming). It is a key active in the SKINDERMA Cellulite Combo and works synergistically with lipolytic cocktails targeting multiple pathways of fat metabolism and cellulite remodeling.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Caffeine 10% is formulated for licensed aesthetic practitioners, dermatologists, and body contouring specialists performing anti-cellulite mesotherapy and microneedling protocols. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753105293626,"sku":"SKD 1041","price":72.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/caffeine.jpg?v=1755599626"},{"product_id":"skinderma-dmae-ampoules-20-x-5ml","title":"SKINDERMA DMAE Ampoules – Lifting, Firming \u0026 Anti-Aging Microneedling Mesotherapy","description":"\u003cp\u003eSKINDERMA DMAE is a professional microneedling mesotherapy solution with a powerful lifting and firming effect on face and body. It tones sagging skin, stimulates collagen and elastin formation, and protects against free radical damage — making it ideal for anti-aging and skin renewal protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly lifts and firms sagging skin on face and neck\u003c\/li\u003e\n\u003cli\u003eTones and renews skin texture for a smoother appearance\u003c\/li\u003e\n\u003cli\u003eDeeply moisturizes and protects against free radical damage\u003c\/li\u003e\n\u003cli\u003eStimulates collagen and elastin formation\u003c\/li\u003e\n\u003cli\u003eHelps prevent premature skin aging and sagging\u003c\/li\u003e\n\u003cli\u003eSupports hair loss and scar treatment protocols\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDimethylaminoethanol Tartrate (DMAE)\u003c\/strong\u003e — a naturally occurring compound present in small amounts in the brain and in marine sources such as anchovies and sardines. DMAE is a precursor to choline, which is required for the synthesis of acetylcholine — the neurotransmitter responsible for muscle contraction and tone. In mesotherapy protocols, DMAE increases acetylcholine availability in the dermis, enhancing the tone of the underlying facial musculature and producing a visible lifting and firming effect on lax, sagging skin. Additionally, DMAE stabilizes cell membranes by incorporating into phospholipid bilayers, reducing membrane fluidity, protecting against oxidative damage from free radicals, and improving the structural integrity of skin cells. This dual mechanism — neuromuscular toning and membrane stabilization — makes DMAE one of the most effective non-surgical lifting actives available in professional aesthetic medicine. It also has applications in hair loss protocols (supporting scalp microcirculation) and scar remodeling treatments.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Wrinkles, anti-aging, dry skin, smoker’s skin, hair loss, and scars\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is DMAE and how does it lift and firm skin?\u003c\/strong\u003e DMAE (Dimethylaminoethanol) is a naturally occurring choline precursor that increases acetylcholine synthesis in the dermis. Acetylcholine is the neurotransmitter responsible for muscle contraction and tone — by boosting its availability in the dermal tissue, DMAE enhances the tone of facial muscles and connective tissue, producing a visible lifting and firming effect on sagging skin. It also stabilizes cell membrane phospholipids, reducing oxidative damage and improving skin cell integrity for a more resilient, youthful complexion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow is DMAE mesotherapy different from surgical lifting?\u003c\/strong\u003e DMAE mesotherapy achieves its lifting effect through biochemical stimulation — increasing acetylcholine-mediated muscle tone and stabilizing skin cell membranes — rather than mechanical tissue repositioning. It is a non-invasive, progressive treatment that improves skin firmness, texture, and elasticity over a course of sessions, making it an effective non-surgical alternative for patients with early to moderate skin laxity who wish to avoid surgical intervention.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does DMAE address?\u003c\/strong\u003e DMAE is recommended for sagging and lax skin, loss of facial definition, wrinkles and expression lines, smoker’s skin (with impaired microcirculation and collagen degradation), dry and dull skin, hair thinning, and post-procedural scar remodeling. Its versatility across facial rejuvenation, scalp, and body protocols makes it one of the most multi-functional actives in the mesotherapy practitioner’s toolkit.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA DMAE is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing microneedling and mesotherapy protocols for lifting, firming, and anti-aging. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753185575226,"sku":"SKD 1043","price":81.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/dmae.jpg?v=1755601162"},{"product_id":"skinderma-exo-ageless-5-x-10ml","title":"SKINDERMA EXO AGELESS 5 x 10ml","description":"\u003ch1 data-start=\"58\" data-end=\"104\"\u003e\u003cstrong data-start=\"60\" data-end=\"102\"\u003eSKINDERMA EXO Ageless 5 x 10ml\u003c\/strong\u003e\u003c\/h1\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp data-start=\"105\" data-end=\"155\"\u003e\u003cstrong data-start=\"105\" data-end=\"153\"\u003eInnovative Exosome-Based Anti-Aging Solution\u003c\/strong\u003e\u003c\/p\u003e\n\u003ch2 data-start=\"157\" data-end=\"185\"\u003e\u003c\/h2\u003e\n\u003cp data-start=\"186\" data-end=\"686\"\u003eSKINDERMA EXO Ageless introduces a groundbreaking approach to anti-aging by utilizing exosomes-small extracellular vesicles-as key components in its mechanism of action. Sourced from plant cells and Lactobacillus, these exosomes serve as microscopic carriers that deliver active ingredients directly to skin cells, initiating regenerative and revitalizing processes. This meticulously formulated treatment aims to rejuvenate the skin holistically and effectively, addressing visible signs of aging.\u003c\/p\u003e\n\u003ch4 data-start=\"688\" data-end=\"709\"\u003e\u003cstrong data-start=\"691\" data-end=\"707\"\u003eKey Benefits\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul data-start=\"710\" data-end=\"1053\"\u003e\n\u003cli data-start=\"710\" data-end=\"821\"\u003e\n\u003cstrong data-start=\"712\" data-end=\"742\"\u003eAdvanced Skin Rejuvenation\u003c\/strong\u003e - Harnesses the power of exosomes to promote skin regeneration and vitality.\u003c\/li\u003e\n\u003cli data-start=\"822\" data-end=\"940\"\u003e\n\u003cstrong data-start=\"824\" data-end=\"852\"\u003eTargeted Delivery System\u003c\/strong\u003e - Ensures precise transport of active ingredients to skin cells for optimal efficacy.\u003c\/li\u003e\n\u003cli data-start=\"941\" data-end=\"1053\"\u003e\n\u003cstrong data-start=\"943\" data-end=\"971\"\u003eComprehensive Anti-Aging\u003c\/strong\u003e - Addresses multiple signs of aging, including wrinkles and loss of elasticity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-start=\"1055\" data-end=\"1082\"\u003e\u003cstrong data-start=\"1058\" data-end=\"1080\"\u003eActive Ingredients\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul data-start=\"1083\" data-end=\"1382\"\u003e\n\u003cli data-start=\"1083\" data-end=\"1182\"\u003e\n\u003cstrong data-start=\"1085\" data-end=\"1124\"\u003eLactobacillus Extracellular Vesicle\u003c\/strong\u003e - Delivers beneficial compounds to support skin health.\u003c\/li\u003e\n\u003cli data-start=\"1183\" data-end=\"1270\"\u003e\n\u003cstrong data-start=\"1185\" data-end=\"1223\"\u003eGalactomyces Extracellular Vesicle\u003c\/strong\u003e - Enhances skin's natural renewal processes.\u003c\/li\u003e\n\u003cli data-start=\"1271\" data-end=\"1382\"\u003e\n\u003cstrong data-start=\"1273\" data-end=\"1331\"\u003eNicotiana Benthamiana \u003c\/strong\u003e-  Plant-based biotechnology to produce bioactive proteins and peptides that can support skin regeneration and repair. May enhance wound healing and skin rejuvenation.\u003c\/li\u003e\n\u003cli data-start=\"1271\" data-end=\"1382\"\u003e\n\u003cstrong data-start=\"1273\" data-end=\"1331\"\u003eHexapeptide-40 \u003c\/strong\u003e- A bioactive peptide that helps reduce fine lines, improves skin elasticity, and supports collagen synthesis for firmer, youthful-looking skin.\u003c\/li\u003e\n\u003cli data-start=\"1271\" data-end=\"1382\"\u003e\n\u003cstrong data-start=\"1273\" data-end=\"1331\"\u003eSh-Oligopeptide-1\u003c\/strong\u003e \u003cstrong\u003e(EGF) \u003c\/strong\u003e- Stimulates cell renewal, boosts collagen production, and accelerates wound healing, making it ideal for anti-aging and post-procedure skin recovery.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-start=\"1384\" data-end=\"1404\"\u003e\u003cstrong data-start=\"1387\" data-end=\"1402\"\u003eIndications\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul data-start=\"1405\" data-end=\"1512\"\u003e\n\u003cli data-start=\"1405\" data-end=\"1452\"\u003eSuitable for mature, damaged, and dry skin.\u003c\/li\u003e\n\u003cli data-start=\"1453\" data-end=\"1512\"\u003eEffective in treating deep wrinkles and signs of aging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-start=\"1514\" data-end=\"1537\"\u003e\u003cstrong data-start=\"1517\" data-end=\"1535\"\u003eTreatment Area\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul data-start=\"1538\" data-end=\"1546\"\u003e\n\u003cli data-start=\"1538\" data-end=\"1546\"\u003eFace\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch4 data-start=\"1548\" data-end=\"1569\"\u003e\u003cstrong data-start=\"1551\" data-end=\"1567\"\u003ePresentation\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eBox containing \u003cstrong data-start=\"1587\" data-end=\"1619\"\u003e5 sterile vials of 10ml each\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cstrong\u003e\u003cb\u003eRecommended For:  \u003c\/b\u003e\u003c\/strong\u003eMature Skin, Damaged and dry skin, skin deep wrinkles.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cstrong\u003e\u003cb\u003eActive Ingredients:  \u003c\/b\u003e\u003c\/strong\u003eLactobacillus Extracellular Visicle, Galactomyces Extracellular Visicle, Nicotiana Benthamiana, Hexapeptide-40, Sh-Oligopeptide-1 (EGF)\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cstrong\u003e\u003cb\u003eTreatment Area:  \u003c\/b\u003e\u003c\/strong\u003eFace\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003cstrong\u003e\u003cb\u003ePresentation:\u003c\/b\u003e\u003c\/strong\u003e  5 x 10ml\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/mesotherapy-solutions.com\/wp-content\/uploads\/2025\/05\/SKINDERMA-Catalog.pdf\"\u003eComplete line of SKINDERMA Product Catalog\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n","brand":"Mesotherapy.ca","offers":[{"title":"Default Title","offer_id":51753220079930,"sku":"SKD 2003","price":120.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/ageless-exo_5f942204-4a05-4bd2-9e19-0057f0624413.jpg?v=1790139431"},{"product_id":"skinderma-h-aura-0-55-5-x-10ml-vials","title":"SKINDERMA H-Aura 0.55 Skin Booster – Multi-Active Rejuvenating Microneedling Mesotherapy 5 x 10ml","description":"\u003cp\u003eSKINDERMA H-Aura 0.55 is a potent professional skin booster delivering a specialized blend of peptides, amino acids, antioxidants, and hyaluronic acid to deeply rejuvenate and revitalize the complexion. Formulated for precision aesthetic procedures, it targets mature, damaged, and dehydrated skin with a comprehensive multi-active formula that addresses hydration, firmness, brightness, and cellular renewal simultaneously.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDeeply hydrates and plumps skin with Sodium Hyaluronate\u003c\/li\u003e\n\u003cli\u003eBoosts elasticity and firmness with 4 peptides and 11 amino acids\u003c\/li\u003e\n\u003cli\u003eBrightens and evens skin tone with Vitamin C (Ascorbic Acid)\u003c\/li\u003e\n\u003cli\u003eProtects against oxidative stress with Vitamin E (Tocopherol)\u003c\/li\u003e\n\u003cli\u003eReduces pore appearance and refines skin texture\u003c\/li\u003e\n\u003cli\u003eSupports skin renewal with Retinol and Succinic Acid\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e4 Peptides\u003c\/strong\u003e — bioactive signal peptides that communicate directly with skin cells to stimulate collagen and elastin production, improve skin firmness, and support structural renewal of the extracellular matrix. Delivered intradermally, peptides reach the dermis at concentrations far exceeding what topical application can achieve.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e11 Amino Acids\u003c\/strong\u003e — the fundamental building blocks of collagen, elastin, and keratin. Intradermal delivery replenishes the amino acid pool available to fibroblasts, directly supporting the synthesis of structural skin proteins and accelerating tissue repair and regeneration.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate\u003c\/strong\u003e — attracts and retains water deep within the dermis, restoring volume, hydration, and skin plumpness. Intradermal delivery at 0.55% concentration provides targeted dermal hydration that topical HA cannot replicate.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAscorbic Acid (Vitamin C)\u003c\/strong\u003e — a potent antioxidant and essential cofactor in collagen biosynthesis. Vitamin C neutralizes free radicals, inhibits melanin synthesis for brightening, and is required for the hydroxylation of proline and lysine — key steps in collagen cross-linking and stability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTocopherol (Vitamin E)\u003c\/strong\u003e — a lipid-soluble antioxidant that protects cell membranes from oxidative damage, works synergistically with Vitamin C to regenerate antioxidant capacity, and supports skin barrier integrity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRetinol (Vitamin A)\u003c\/strong\u003e — stimulates fibroblast activity, accelerates cell turnover, and upregulates collagen synthesis. At the dermal level via mesotherapy, Retinol promotes skin renewal and improves texture, fine lines, and overall skin quality without the surface irritation associated with topical retinoid use.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSuccinic Acid\u003c\/strong\u003e — a naturally occurring metabolic intermediate in the Krebs cycle that energizes skin cells, stimulates fibroblast activity, and has soothing anti-inflammatory properties. It supports cellular energy production and enhances the overall regenerative effect of the formula.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Mature skin, damaged skin, dehydration, pore reduction, and elasticity improvement\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA H-Aura 0.55 and what does it treat?\u003c\/strong\u003e H-Aura 0.55 is a professional multi-active skin booster combining 4 peptides, 11 amino acids, Sodium Hyaluronate, Vitamins A, C, and E, and Succinic Acid in a single mesotherapy vial. It is designed for comprehensive skin rejuvenation, addressing dehydration, loss of firmness and elasticity, dull and uneven skin tone, enlarged pores, and overall signs of skin aging and damage in a single treatment protocol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is intradermal delivery of vitamins and peptides more effective than topical?\u003c\/strong\u003e Vitamins C and A, peptides, and amino acids face significant barriers to dermal penetration when applied topically — the stratum corneum limits absorption to a fraction of the applied dose, and many actives degrade before reaching the dermis. Delivered intradermally via mesotherapy or microneedling, H-Aura 0.55 bypasses these barriers entirely, delivering bioactive concentrations of every ingredient directly to the fibroblasts and cellular structures where they have their greatest effect.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Succinic Acid work alongside peptides and vitamins in this formula?\u003c\/strong\u003e Succinic Acid is a key intermediate in the Krebs cycle — the cellular energy production pathway. By supporting mitochondrial energy output in skin cells, it enhances the metabolic capacity of fibroblasts to respond to the peptide and vitamin signals in the formula, amplifying collagen synthesis, cellular repair, and overall regenerative activity. Its anti-inflammatory properties also help reduce post-procedure skin reactivity.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA H-Aura 0.55 is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional multi-active skin booster, mesotherapy, and microneedling rejuvenation protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753246359866,"sku":"SKD 1140","price":233.8,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/aura.jpg?v=1755601999"},{"product_id":"skinderma-hyaluronic-acid-3-5-5-x-5ml-vials","title":"SKINDERMA Hyaluronic Acid 3.5% Professional Microneedling Mesotherapy Cocktail","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Hyaluronic Acid 3.5% 5 x 5ml\u003c\/strong\u003e is a professional-grade microneedling mesotherapy vial delivering an intensive concentration of Sodium Hyaluronate directly into the skin. At 3.5%, this high-potency formula deeply replenishes and maintains the skin’s moisture levels, restoring a plump, supple, and youthful appearance.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDeeply hydrates and plumps dry, dehydrated skin\u003c\/li\u003e\n\u003cli\u003eVisibly reduces the appearance of wrinkles and expression lines\u003c\/li\u003e\n\u003cli\u003eImproves skin elasticity and firmness\u003c\/li\u003e\n\u003cli\u003eSupports tissue restructuring and repair of damaged skin\u003c\/li\u003e\n\u003cli\u003eHelps slow the visible signs of aging by supporting fibroblast activity and collagen formation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate (3.5%)\u003c\/strong\u003e — the sodium salt form of hyaluronic acid, naturally present in the dermis and responsible for maintaining skin hydration, volume, and structural integrity. Sodium Hyaluronate has an extraordinary water-retention capacity — binding up to 1,000 times its own weight in water — making it the most effective natural humectant available in aesthetic medicine. At 3.5% professional concentration, delivered intradermally via mesotherapy or microneedling, it provides a level of dermal hydration that topical HA formulations cannot achieve, as they are unable to penetrate to the depth of the dermis. Beyond hydration, Sodium Hyaluronate at this concentration also stimulates fibroblast activity and collagen synthesis, improving skin density, elasticity, and firmness over a course of treatments. The result is visibly plumper, smoother, more resilient skin with reduced wrinkle depth and improved overall skin quality.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Dry and aging skin, dehydrated skin, wrinkles and expression lines\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 5ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat makes SKINDERMA Hyaluronic Acid 3.5% different from topical HA serums?\u003c\/strong\u003e Topical hyaluronic acid serums act primarily on the skin surface, as HA molecules are too large to penetrate the dermis effectively. SKINDERMA HA 3.5%, delivered intradermally via mesotherapy or microneedling, bypasses this barrier entirely — depositing a high concentration of Sodium Hyaluronate directly into the dermis where it can bind water, restore volume, and stimulate fibroblasts and collagen synthesis at the cellular level. The result is deep, lasting hydration that topical products cannot replicate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is 3.5% a significant HA concentration for mesotherapy?\u003c\/strong\u003e Most skin booster products and HA mesotherapy vials contain between 0.5% and 2% Sodium Hyaluronate. At 3.5%, SKINDERMA delivers a markedly higher hyaluronic acid load per treatment session, providing more intensive hydration, more pronounced plumping and volume restoration, and a stronger stimulus for fibroblast activity and collagen production — making it particularly suited for dehydrated, mature, or environmentally damaged skin requiring intensive rejuvenation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does HA 3.5% mesotherapy treat?\u003c\/strong\u003e This formula is recommended for dry and chronically dehydrated skin, fine lines and wrinkles caused by moisture loss, loss of skin elasticity and firmness, dull and tired-looking skin, and post-procedure skin recovery. It is also used as a foundational hydration step in combination mesotherapy protocols alongside peptides, vitamins, and regenerative actives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Hyaluronic Acid 3.5% is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional microneedling and mesotherapy hydration and rejuvenation protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51753275949370,"sku":"SKD 1061","price":266.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/hyaluronicacid_s.jpg?v=1755602573"},{"product_id":"skinderma-laureth-9-ampoules-20-x-2ml","title":"SKINDERMA Laureth-9 ampoules 20 x 2ml","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Laureth-9 ampoules 20 x 2ml\u003c\/strong\u003e is a professional sclerotherapy and vascular mesotherapy solution used to treat spider veins, couperose, and vascular skin conditions. Laureth-9 works by disrupting the lipid layer of vessel walls, making it an effective therapy for sclerosis and superficial vascular irregularities, while also providing moisturizing benefits to the epidermis.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eEffective therapy for spider veins (vascular spiders) and couperose\u003c\/li\u003e\n\u003cli\u003eSupports treatment of sclerosis and superficial vascular irregularities\u003c\/li\u003e\n\u003cli\u003eHelps retain moisture through the stratum corneum\u003c\/li\u003e\n\u003cli\u003eMoisturizes the lipid layer and epidermis\u003c\/li\u003e\n\u003cli\u003eHelps improve the appearance of varicose veins\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLaureth-9\u003c\/strong\u003e — a non-ionic surfactant that disrupts the phospholipid membrane of vessel walls when delivered intradermally via sclerotherapy. This causes endothelial damage and fibrosis of the targeted vessel, leading to its gradual collapse and reabsorption. Laureth-9 is an established sclerosing agent used in professional protocols for spider veins, telangiectasias, couperose, and superficial vascular lesions. It also exhibits mild moisturizing properties for the surrounding epidermis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Sclerosis, spider veins, couperose, stretch marks\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 2ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA Laureth-9 Sclerotherapy?\u003c\/strong\u003e SKINDERMA Laureth-9 is a professional sclerotherapy and vascular mesotherapy ampoule containing Laureth-9, a non-ionic surfactant sclerosing agent. Presented as 20 x 2ml ampoules, it is clinically formulated to treat spider veins, telangiectasias, couperose, and superficial vascular lesions by disrupting vessel wall membranes and inducing controlled fibrosis and reabsorption of the targeted vessels.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Laureth-9 work for spider veins and couperose?\u003c\/strong\u003e Laureth-9 acts as a chemical sclerosing agent by disrupting the phospholipid membrane integrity of endothelial cells lining the vessel walls. When performing the treatment, it causes localized endothelial damage, triggering an inflammatory response and subsequent fibrosis that gradually collapses and eliminates the targeted superficial vessel. This makes it effective for spider veins, telangiectasias, and visible couperose on the face and body.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat vascular conditions does Laureth-9 treat?\u003c\/strong\u003e SKINDERMA Laureth-9 is recommended for spider veins (telangiectasias), couperose, superficial vascular irregularities, and visible small varicose veins. It is used in professional sclerotherapy and vascular mesotherapy protocols by licensed aesthetic practitioners and phlebology specialists.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Laureth-9 is formulated for licensed aesthetic practitioners, dermatologists, phlebologists, and vascular treatment specialists performing professional sclerotherapy protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51758018789690,"sku":"SKD 1045","price":58.99,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/laureth-9.jpg?v=1755679986"},{"product_id":"skinderma-lyophilized-exo-ageless-5-x-1500-ui","title":"SKINDERMA LYOPHILIZED EXO AGELESS EXOSOME 5 x 1500 UI","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA LYOPHILIZED EXO-AGELESS 5 x 1500 UI\u003c\/strong\u003e is a premium professional-grade exosome treatment in \u003cstrong\u003elyophilized (freeze-dried) form\u003c\/strong\u003e — preserving the delicate bioactive structure of exosomes for maximum potency and stability. This advanced anti-aging formula uses exosomes as microscopic extracellular vesicles extracted from plant cells and Lactobacillus, acting as precision delivery vehicles that transport active ingredients directly to skin cells to trigger deep regenerative and revitalizing processes.\u003c\/p\u003e\n\u003cp\u003eThe lyophilized format ensures shelf stability and bioavailability compared to liquid formulations, making it the preferred choice for discerning aesthetic professionals performing anti-aging microneedling and mesotherapy protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly reduces deep wrinkles and fine lines\u003c\/li\u003e\n\u003cli\u003eFirms and restores skin elasticity on face and neck\u003c\/li\u003e\n\u003cli\u003eDeeply hydrates dry and damaged skin\u003c\/li\u003e\n\u003cli\u003ePromotes cellular regeneration and renewal\u003c\/li\u003e\n\u003cli\u003eSuperior potency preserved through freeze-drying technology\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactobacillus Extracellular Vesicles (Exosomes)\u003c\/strong\u003e — probiotic-derived nano-vesicles that deliver growth factors, microRNA, and signaling proteins directly into skin cells, rebalancing the skin microbiome, reducing inflammation, and activating regenerative pathways in aged or damaged dermis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGalactomyces Extracellular Vesicles (Exosomes)\u003c\/strong\u003e — ferment-derived exosomes that brighten skin tone, refine pores, and support fibroblast activity and cellular metabolism for overall skin quality improvement.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNicotiana Benthamiana Hexapeptide-40\u003c\/strong\u003e — a plant-derived neuromodulating peptide that visibly softens expression lines and deep wrinkles by inhibiting neuromuscular signal transmission at the dermal level — a powerful non-invasive adjunct in anti-aging mesotherapy protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSh-Oligopeptide-1 (EGF — Epidermal Growth Factor)\u003c\/strong\u003e — a recombinant human Epidermal Growth Factor that binds to EGF receptors on keratinocytes and fibroblasts, stimulating cell proliferation, collagen and elastin synthesis, and accelerating tissue repair. EGF is one of the most extensively researched bioactives in regenerative medicine, clinically recognized for its ability to restore skin density, smooth texture, and accelerate post-procedure recovery.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Mature skin, damaged and dry skin, deep wrinkles\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 1500 UI lyophilized vials\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA EXO-AGELESS and how does it work?\u003c\/strong\u003e SKINDERMA EXO-AGELESS is a professional lyophilized exosome anti-aging treatment combining Lactobacillus and Galactomyces extracellular vesicles with EGF (Sh-Oligopeptide-1) and a plant-derived  peptide. The exosomes act as precision delivery vehicles, transporting growth factors and signaling molecules directly into skin cells to activate collagen synthesis, cellular regeneration, and tissue repair — delivering results that topical formulations cannot achieve.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat makes EGF (Sh-Oligopeptide-1) effective for anti-aging?\u003c\/strong\u003e EGF (Epidermal Growth Factor) is a naturally occurring protein that binds to specific receptors on skin cells, triggering a cascade of proliferative and regenerative processes. It stimulates the production of new keratinocytes and fibroblasts, accelerates collagen and elastin synthesis, and promotes tissue repair. At the concentrations achieved in professional microneedling\/mesotherapy protocols, EGF reaches the dermis far more effectively than topical EGF serums — making it one of the most potent anti-aging actives available to aesthetic professionals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does EXO-AGELESS address?\u003c\/strong\u003e This formula is recommended for mature skin with deep wrinkles and expression lines, loss of firmness and elasticity, dry and damaged skin, dull complexion, and skin requiring intensive regeneration or post-procedure recovery support. The combination of exosomes, EGF, and the neuromodulating peptide provides a comprehensive multi-pathway anti-aging action.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA EXO-AGELESS is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional anti-aging microneedling and mesotherapy protocols. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51758045888826,"sku":"SKD 2006","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/EXO-AGELESS_1500UI_ef9cecc0-4144-4989-b5f8-638deda54a5b.jpg?v=1755681461"},{"product_id":"skinderma-lyophilized-exo-hair-5-x-1500-ui","title":"SKINDERMA LYOPHILIZED EXO HAIR EXOSOME 5 x 1500 UI","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA LYOPHILIZED EXO-HAIR 5 x 1500 UI\u003c\/strong\u003e is a premium professional-grade hair restoration treatment in \u003cstrong\u003elyophilized exosome form\u003c\/strong\u003e — preserving the delicate bioactive structure of exosomes for maximum potency and stability. This advanced formula incorporates a unique synergy of exosomes and targeted active ingredients, delivering them directly to hair follicle cells to stimulate growth, strengthen roots, and restore scalp vitality.\u003c\/p\u003e\n\u003cp\u003eThe lyophilized (freeze-dried) format ensures superior shelf stability and bioavailability compared to liquid formulations, making it the preferred choice for aesthetic professionals performing scalp mesotherapy and microneedling hair restoration protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eStimulates hair follicle activity and promotes hair regrowth\u003c\/li\u003e\n\u003cli\u003eAddresses androgenic alopecia and diffuse hair loss\u003c\/li\u003e\n\u003cli\u003eStrengthens hair roots and visibly reduces shedding\u003c\/li\u003e\n\u003cli\u003eRevitalizes and nourishes the scalp\u003c\/li\u003e\n\u003cli\u003eSuperior potency preserved through freeze-drying technology\u003c\/li\u003e\n\u003cli\u003eSupports hair density and thickness\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactobacillus Extracellular Vesicles (Exosomes)\u003c\/strong\u003e — probiotic-derived nano-vesicles that carry bioactive signaling molecules including growth factors, microRNA, and proteins directly into hair follicle cells. They rebalance the scalp microbiome, reduce follicular inflammation, and activate resting (telogen) follicles back into the active growth (anagen) phase.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGalactomyces Extracellular Vesicles (Exosomes)\u003c\/strong\u003e — ferment-derived exosomes rich in nutrients and growth-stimulating signals that support follicle cell metabolism, strengthen the dermal papilla, and enhance follicle regeneration capacity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBiotinoyl Tripeptide-1\u003c\/strong\u003e — a biotin-anchored peptide complex that strengthens the hair anchoring mechanism at the follicle level, reduces shedding, and stimulates follicle proliferation and hair shaft growth.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePhospholipids\u003c\/strong\u003e — essential structural components that nourish and reinforce the hair follicle membrane, supporting cellular integrity and the uptake of active ingredients into follicle cells.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Scalp \u0026amp; Hair\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Androgenic alopecia, diffuse hair loss, thinning hair\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 1500 UI lyophilized vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eReconstitution\u003c\/h2\u003e\n\u003cp\u003eBefore use, reconstitute the lyophilized powder by adding the appropriate volume of sterile saline (0.9% NaCl) or sterile water or another sterile hair cocktail for reconstitution to the vial. Gently swirl until fully dissolved. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat are exosomes and how do they work for hair restoration?\u003c\/strong\u003e Exosomes are nano-sized extracellular vesicles naturally secreted by cells to carry signaling molecules — including growth factors, microRNA, and proteins — between cells. In hair restoration, exosomes derived from Lactobacillus and Galactomyces deliver these bioactive signals directly into hair follicle cells, activating dormant follicles, stimulating the dermal papilla, reducing inflammation, and promoting the transition from the resting (telogen) phase back into active growth (anagen).\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is the lyophilized (freeze-dried) format superior for exosome treatments?\u003c\/strong\u003e Lyophilization (freeze-drying) preserves the structural integrity and bioactivity of exosomes far more effectively than liquid formulations, which can degrade over time and lose potency. The lyophilized format extends shelf life, maintains the full concentration of active signaling molecules, and ensures maximum efficacy when reconstituted just before treatment — making it the gold standard for professional exosome-based aesthetic protocols.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat types of hair loss does EXO-HAIR address?\u003c\/strong\u003e SKINDERMA EXO-HAIR is recommended for androgenic alopecia (male and female pattern hair loss), diffuse hair thinning, telogen effluvium, and scalp conditions associated with inflammation and follicle miniaturization. Its multi-pathway approach — combining exosome cell signaling, peptide anchoring, and microbiome support — makes it one of the most comprehensive professional hair restoration treatments available.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Lyophilized EXO-HAIR is formulated for licensed aesthetic practitioners, trichologists, dermatologists, and hair restoration specialists performing scalp mesotherapy and microneedling protocols.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51758058078522,"sku":"SKD 2008","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/eXO-HAIR1500UI.jpg?v=1755681848"},{"product_id":"skinderma-organic-silicium-ampoules-20-x-5ml","title":"SKINDERMA Organic Silicium Ampoules – Collagen \u0026 Elastin Firming Microneedling Mesotherapy","description":"\u003cp\u003eSKINDERMA Organic Silicium is a professional microneedling mesotherapy solution that smooths, tones, and firms the skin by strengthening collagen and elastin fibres in connective tissue — helping to slow the visible signs of aging.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eStrengthens, stretches, and supports collagen and elastin fibres\u003c\/li\u003e\n\u003cli\u003eFirms and tones skin for a visibly lifted appearance\u003c\/li\u003e\n\u003cli\u003eDeeply moisturizes and regenerates skin cells\u003c\/li\u003e\n\u003cli\u003eSlows the aging process and improves skin texture\u003c\/li\u003e\n\u003cli\u003eReduces the appearance of stretch marks\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylsilanol Mannuronate (Organic Silicium)\u003c\/strong\u003e — an organic, bioavailable form of silicon derived from marine algae (mannuronic acid). Silicon is a critical trace element for connective tissue health, playing a direct role in the synthesis and cross-linking of collagen and elastin fibres. When delivered intradermally via mesotherapy, Methylsilanol Mannuronate stimulates fibroblast activity, reinforces the extracellular matrix, improves skin elasticity and firmness, and supports the repair of stretch marks and lax skin. Its organic form ensures superior bioavailability and tolerability compared to inorganic silicon compounds.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Aging skin, loss of firmness, skin regeneration, and stretch marks\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Organic Silicium (Methylsilanol Mannuronate) in mesotherapy?\u003c\/strong\u003e Organic Silicium, or Methylsilanol Mannuronate, is a bioavailable marine-derived form of silicon used in professional mesotherapy protocols. Silicon is an essential trace element for connective tissue integrity — it directly participates in collagen and elastin synthesis and cross-linking. Delivered intradermally, it stimulates fibroblasts, reinforces the extracellular matrix, and restores skin firmness and elasticity lost through aging or mechanical stress.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Organic Silicium firm and tone the skin?\u003c\/strong\u003e Methylsilanol Mannuronate activates fibroblasts and supports the structural cross-linking of collagen and elastin fibres in the dermis. This reinforces the skin’s connective tissue scaffold, improving firmness, elasticity, and tone. Its moisturizing action also helps maintain dermal hydration, contributing to a smoother, more supple skin texture.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does Organic Silicium treat?\u003c\/strong\u003e This ampoule is recommended for sagging and lax skin, loss of firmness and elasticity, skin aging, rough or thin skin texture, and stretch marks. Its connective tissue-strengthening action makes it effective for both facial rejuvenation and body treatment protocols.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Organic Silicium is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing microneedling and mesotherapy protocols for skin firming and connective tissue regeneration. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51758094287162,"sku":"SKD 1049","price":63.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/organicsilicium.jpg?v=1755682142"},{"product_id":"skinderma-pdrn-ha-1-5-x-5ml-vials","title":"SKINDERMA PDRN + HA 1% Professional Microneedling Mesotherapy Skin Booster","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA PDRN + HA 1% 5 x 5ml\u003c\/strong\u003e is a powerful regenerative microneedling mesotherapy ampoule combining two of the most clinically recognized skin repair actives: \u003cstrong\u003ePDRN (Polydeoxyribonucleotide)\u003c\/strong\u003e and \u003cstrong\u003eSodium Hyaluronate (1%)\u003c\/strong\u003e. Together they deliver deep regenerative, reparative, and anti-aging capabilities, restoring damage from within and revitalizing the skin’s natural structure.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eRestores damage caused deep within the skin layers\u003c\/li\u003e\n\u003cli\u003eVisibly improves skin elasticity and firmness\u003c\/li\u003e\n\u003cli\u003eStimulates collagen and elastin synthesis for a more youthful appearance\u003c\/li\u003e\n\u003cli\u003eDeeply hydrates dry and dehydrated skin\u003c\/li\u003e\n\u003cli\u003eSupports repair of skin imperfections and damaged tissue\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePDRN (Polydeoxyribonucleotide)\u003c\/strong\u003e — a highly purified DNA-derived molecule extracted from salmon sperm DNA, PDRN activates A2A adenosine receptors in skin tissue, triggering a cascade of regenerative processes including collagen synthesis, fibroblast proliferation, and angiogenesis. It also has anti-inflammatory properties that support tissue repair in damaged, stressed, or post-procedure skin. PDRN is one of the most researched biorevitalizing actives in aesthetic medicine, widely used in skin boosters and wound healing protocols.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate (1%)\u003c\/strong\u003e — a highly biocompatible form of hyaluronic acid that attracts and retains moisture deep within the dermis, restoring hydration, volume, and elasticity. At 1% concentration delivered via mesotherapy, it provides immediate plumping and long-lasting hydration superior to topical application.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Anti-aging treatments, damaged and dry skin, skin imperfections\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 5ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is PDRN and how does it work in mesotherapy?\u003c\/strong\u003e PDRN (Polydeoxyribonucleotide) is a purified DNA-derived molecule extracted from salmon DNA that activates A2A adenosine receptors in skin tissue. This triggers fibroblast proliferation, collagen synthesis, and angiogenesis — repairing damaged tissue from within. Delivered via mesotherapy, PDRN provides a powerful regenerative stimulus that topical products cannot replicate, making it one of the most effective biorevitalizing actives in professional aesthetic medicine.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does PDRN + HA treat?\u003c\/strong\u003e This combination is recommended for aging and lax skin, dehydrated and dry skin, damaged or stressed skin, skin imperfections, post-procedure recovery, and overall loss of radiance and elasticity. The dual action of PDRN’s cellular repair and Hyaluronate’s deep hydration makes it one of the most complete skin booster formulas available.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy combine PDRN with Hyaluronic Acid?\u003c\/strong\u003e PDRN and Sodium Hyaluronate work synergistically — PDRN stimulates the biological repair and regeneration of skin cells and collagen fibers, while Hyaluronate provides the hydration and volume necessary to restore skin structure and suppleness. Together, they address both the cellular and structural dimensions of skin aging and damage in a single treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA PDRN + HA 1% is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing microneedling and mesotherapy skin booster protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51758100807994,"sku":"SKD 1104","price":126.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/PDRN_HA.jpg?v=1755682654"},{"product_id":"skinderma-protease-5-x-10ml-vials","title":"SKINDERMA Protease 5 x 10ml vials","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Protease 15% 5 x 10ml\u003c\/strong\u003e is a professional enzyme-based mesotherapy solution that increases cell renewal and skin regeneration. By breaking down protein bonds in the skin, Protease enables a variety of therapeutic applications — from smoothing fine lines and improving skin texture to enhancing hydration and supporting overall skin regeneration.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eIncreases cell renewal and accelerates skin regeneration\u003c\/li\u003e\n\u003cli\u003eVisibly improves skin relief and reduces the appearance of wrinkles\u003c\/li\u003e\n\u003cli\u003eBreaks down protein bonds to allow deeper therapeutic action\u003c\/li\u003e\n\u003cli\u003eImproves skin texture and smoothness\u003c\/li\u003e\n\u003cli\u003eEnhances skin hydration and regeneration\u003c\/li\u003e\n\u003cli\u003eSuitable for all skin types\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eProtease (15%)\u003c\/strong\u003e — a proteolytic enzyme that catalyzes the breakdown of protein bonds in the skin, stimulating cell renewal, improving skin texture and surface smoothness, and supporting regeneration and hydration. At 15% professional concentration delivered via mesotherapy, it enables deeper enzymatic action than topical formulations, accelerating the skin’s natural renewal cycle and improving the efficacy of accompanying actives.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e All skin types, fine lines, skin texture improvement, skin hydration and regeneration\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA Protease 15% Mesotherapy?\u003c\/strong\u003e SKINDERMA Protease 15% is a professional enzyme-based mesotherapy solution containing Protease at 15% concentration, presented as 5 x 10ml vials. Protease is a proteolytic enzyme that breaks down protein bonds in the skin to accelerate cell renewal, improve texture, reduce wrinkles, and enhance the skin’s capacity for hydration and regeneration — suitable for all skin types.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Protease work in skin regeneration?\u003c\/strong\u003e Protease catalyzes the enzymatic breakdown of damaged or cross-linked proteins in the dermis, clearing the way for new collagen formation and accelerated cellular turnover. When delivered via mesotherapy at 15% concentration, it acts more deeply and effectively than topical enzymatic treatments, improving skin texture, smoothness, and the absorption and efficacy of other actives used in the same protocol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does Protease treat?\u003c\/strong\u003e SKINDERMA Protease is recommended for fine lines, uneven skin texture, rough or congested skin, dehydration, and skin in need of renewal or regeneration. Its broad enzymatic action makes it a versatile preparatory and regenerative active suitable for inclusion in anti-aging, brightening, and hydration mesotherapy protocols.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Protease 15% is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing microneedling and mesotherapy treatments. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. 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Pyruvic Acid promotes the synthesis of new collagen and elastin fibers, accelerates cellular turnover, and improves skin texture and density. 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It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eProfessional cosmetic use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51758232633658,"sku":"SKD 1057","price":151.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/SodiumDNA.jpg?v=1755684385"},{"product_id":"skinderma-vitamin-b-complex-ampoules-20-x-5ml","title":"SKINDERMA Vitamin B Complex ampoules 20 x 5ml Microneedling Mesotherapy Cocktail","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Vitamin B Complex ampoules 20 x 5ml\u003c\/strong\u003e deliver a comprehensive multi-vitamin infusion directly into the skin, combining six essential B vitamins to promote skin regeneration, repair, and radiance. 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The combination of Galactomyces and Lactobacillus exosomes also supports microbiome balance and overall skin radiance.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA EXO-Whitening is formulated exclusively for licensed aesthetic practitioners and clinics performing microneedling and mesotherapy brightening protocols. It is intended for professional use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. 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This professional-grade microneedling mesotherapy solution combines three clinically recognized brightening actives in a precise synergy for a more even, luminous complexion.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly reduces the appearance of hyperpigmentation and dark spots\u003c\/li\u003e\n\u003cli\u003eHelps even skin tone on face and body\u003c\/li\u003e\n\u003cli\u003eSupports a brighter, more radiant complexion\u003c\/li\u003e\n\u003cli\u003eAddresses the appearance of melasma and acne scars\u003c\/li\u003e\n\u003cli\u003ePowerful antioxidant protection against photo-aging\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTranexamic Acid\u003c\/strong\u003e — visibly reduces melanin production and dark spot appearance\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNicotinamide Mononucleotide (derivative of Vitamin B3)\u003c\/strong\u003e — brightens skin tone, minimizes pores, and supports skin barrier function\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAscorbic Acid (Vitamin C)\u003c\/strong\u003e — potent antioxidant that visibly brightens and protects against oxidative damage\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Hyperpigmentation, dark spots, melasma, acne scars, sun spots\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA Melano Combo?\u003c\/strong\u003e SKINDERMA Melano Combo is a professional brightening mesotherapy cocktail combining Tranexamic Acid, Nicotinamide Mononucleotide (Vitamin B3 derivative), and Ascorbic Acid (Vitamin C). Formulated as 5 x 10ml vials, it is clinically designed to visibly reduce hyperpigmentation, melasma, dark spots, and acne scars on both the face and body through microneedling and mesotherapy protocols.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Tranexamic Acid reduce hyperpigmentation?\u003c\/strong\u003e Tranexamic Acid works by inhibiting the interaction between UV-stimulated keratinocytes and melanocytes, reducing excess melanin production that causes dark spots and melasma. Delivered via mesotherapy directly into the dermis, it achieves more targeted and effective results than topical application alone.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does Melano Combo treat?\u003c\/strong\u003e This formula targets hyperpigmentation disorders, melasma, post-inflammatory dark spots, acne scars, sun spots, and uneven skin tone on both the face and body. The triple-active combination of Tranexamic Acid, Niacinamide, and Vitamin C provides a comprehensive brightening and antioxidant effect.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Melano Combo is formulated exclusively for licensed aesthetic practitioners and clinics performing microneedling and mesotherapy protocols for pigmentation correction. It is intended for professional use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. 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Rich in bioactive compounds, artichoke extract delivers a diuretic and cleansing effect while stimulating the lymphatic system — making it an excellent complement to lipolytic and anti-cellulite mesotherapy protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eHelps treat cellulite and localized fat deposits\u003c\/li\u003e\n\u003cli\u003eStimulates lymphatic drainage for improved fluid elimination\u003c\/li\u003e\n\u003cli\u003eDelivers a natural diuretic and cleansing effect\u003c\/li\u003e\n\u003cli\u003eSupports body remodelling and contouring protocols\u003c\/li\u003e\n\u003cli\u003eNatural plant-derived active ingredient\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCynara scolymus (Artichoke Extract) 2%\u003c\/strong\u003e — a natural plant extract rich in cynarin and chlorogenic acid that supports liver function, lymphatic drainage, fat metabolism, and diuretic action\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Cellulite, localized fat, lymphatic drainage stimulation\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA Artichoke 2% Ampoules?\u003c\/strong\u003e SKINDERMA Artichoke 2% is a professional mesotherapy solution containing Cynara scolymus (artichoke extract) at 2% concentration. Rich in cynarin and chlorogenic acid, it is clinically formulated to stimulate lymphatic drainage, reduce localized fat deposits, and address cellulite through natural diuretic and cleansing action. Presented as 20 x 5ml ampoules for professional use.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does artichoke extract work for cellulite and lymphatic drainage?\u003c\/strong\u003e Artichoke extract contains cynarin, a bioactive compound that stimulates bile production and liver function, supporting the body’s natural fat metabolism and fluid elimination pathways. When delivered via mesotherapy, it enhances lymphatic circulation, reduces fluid retention, and complements lipolytic protocols for visible body contouring results.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat conditions is this treatment recommended for?\u003c\/strong\u003e SKINDERMA Artichoke 2% is recommended for cellulite, lipodystrophy, localized fat deposits, and sluggish lymphatic circulation. It is commonly used alongside lipolytic agents such as Phosphatidylcholine and Sodium Deoxycholate to enhance body sculpting outcomes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e This product is formulated exclusively for licensed aesthetic practitioners, dermatologists, and body contouring specialists performing mesotherapy protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":51763293815098,"sku":"SKD 1047","price":56.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/naturalartichoke.jpg?v=1755776203"},{"product_id":"elixir-aesthetics-centella-exosomes-biorevitalizer-5-x-5ml-vials","title":"Centella Exosomes BioRevitalizer 5×5ml | Mesotherapy \u0026 Microneedling Serum | Elixir Aesthetics","description":"\u003ch3\u003e\u003cstrong\u003eCentella Exosomes BioRevitalizer: Advanced Professional Skin Rejuvenation\u003c\/strong\u003e\u003c\/h3\u003e\n\n\u003cp\u003e\u003cem\u003eCentella Exosomes BioRevitalizer\u003c\/em\u003e by Elixir Aesthetics is a professional-grade, plant-derived biorevitalizing cocktail formulated for mesotherapy and microneedling treatments. It delivers firmer, brighter, and deeply hydrated skin through a clinically active blend of Centella Asiatica Exosomes, Sodium DNA, low-molecular-weight Sodium Hyaluronate, and Panthenol (Pro-Vitamin B5).\u003c\/p\u003e\n\n\u003ch4\u003e\u003cstrong\u003eWho Is This For?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eDesigned exclusively for licensed aesthetic professionals — including dermatologists, cosmetic nurses, medspas, and skin clinics — seeking a high-efficacy biorevitalizer for skin rejuvenation protocols. Ideal for clients presenting with dehydration, loss of elasticity, photo-aging, fine lines, or post-procedure recovery needs.\u003c\/p\u003e\n\n\u003ch4\u003e\u003cstrong\u003eKey Ingredients \u0026amp; Benefits\u003c\/strong\u003e\u003c\/h4\u003e\n\n\u003ch5\u003e\u003cstrong\u003eCentella Asiatica Extract (Asiaticoside)\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eStimulates collagen synthesis for improved skin texture and resilience.\u003c\/li\u003e\n\u003cli\u003eReduces inflammation and supports vascular integrity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch5\u003e\u003cstrong\u003eRosa Centifolia Leaf Cell Extract\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eRich in antioxidants; hydrates and calms post-treatment irritation.\u003c\/li\u003e\n\u003cli\u003eNeutralizes environmental oxidative stressors.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch5\u003e\u003cstrong\u003eCentaurea Cyanus Callus Lysate Extract\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eProtects against oxidative damage and enhances overall skin vitality.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch5\u003e\u003cstrong\u003eSodium DNA \u0026amp; Hydrolyzed DNA\/RNA\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eStimulates cellular regeneration and tissue repair.\u003c\/li\u003e\n\u003cli\u003eDiminishes wrinkles and reverses photo-aging effects.\u003c\/li\u003e\n\u003cli\u003eEnhances cellular turnover for targeted rejuvenation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch5\u003e\u003cstrong\u003eSodium Hyaluronate (Low Molecular Weight)\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eDelivers deep, long-lasting hydration for plump, supple skin.\u003c\/li\u003e\n\u003cli\u003ePromotes elasticity and reduces fine lines and wrinkles.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch5\u003e\u003cstrong\u003ePanthenol (Pro-Vitamin B5)\u003c\/strong\u003e\u003c\/h5\u003e\n\u003cul\u003e\n\u003cli\u003eSoothes and accelerates post-treatment healing.\u003c\/li\u003e\n\u003cli\u003eEnhances elasticity, hydration, and recovery from dermatological conditions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003e\u003cstrong\u003eSkin Revitalization Benefits\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eIntensive Hydration:\u003c\/strong\u003e Low-MW Sodium Hyaluronate ensures long-lasting moisture retention for plump, youthful skin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Renewal:\u003c\/strong\u003e Sodium DNA and Panthenol synergistically repair and regenerate skin tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAntioxidant Defense:\u003c\/strong\u003e Rosa Centifolia and Centaurea Cyanus extracts combat free radical damage.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCollagen Stimulation:\u003c\/strong\u003e Centella Asiatica promotes collagen synthesis, enhancing firmness and elasticity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003e\u003cstrong\u003eTreatment Protocol\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eApplication method:\u003c\/strong\u003e Mesotherapy (needle-free or needle-based) or microneedling (0.5–1.5mm depth).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSession frequency:\u003c\/strong\u003e 1 session per week for 4–6 weeks; maintenance every 4–6 weeks thereafter.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDosage per session:\u003c\/strong\u003e 1 vial (5ml) per treatment area.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombination protocols:\u003c\/strong\u003e Compatible with PRP, PDRN, and post-laser recovery regimens.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003e\u003cstrong\u003eFrequently Asked Questions\u003c\/strong\u003e\u003c\/h4\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhat is Centella Exosomes BioRevitalizer used for?\u003c\/strong\u003e\u003cbr\u003e\nIt is a professional mesotherapy and microneedling serum used to rejuvenate aging, dehydrated, or damaged skin by delivering plant-derived exosomes, Sodium DNA, and Hyaluronate directly into the dermis.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eAre these exosomes plant-derived or human-derived?\u003c\/strong\u003e\u003cbr\u003e\nAll exosomes in this formulation are 100% plant-derived from Asian Centella Asiatica, offering non-immunogenic, skin-compatible bioactivity without the regulatory concerns of human or animal-derived exosomes.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eHow should this product be stored?\u003c\/strong\u003e\u003cbr\u003e\nStore between 15–25°C, away from direct sunlight. Shelf life is up to 3 years under proper storage conditions. Do not freeze.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eIs this product available in Canada?\u003c\/strong\u003e\u003cbr\u003e\nYes. Centella Exosomes BioRevitalizer is distributed in Canada by Elixir Aesthetics Inc. and ships from our Canadian fulfillment center.\u003c\/p\u003e\n\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does this treat?\u003c\/strong\u003e\u003cbr\u003e\nDehydration, loss of elasticity, fine lines, wrinkles, photo-aging, dull complexion, and post-procedure skin recovery.\u003c\/p\u003e\n\n\u003ch4\u003e\u003cstrong\u003eFormulation Specifications\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin-Compatible \u0026amp; Non-Immunogenic:\u003c\/strong\u003e Plant-derived exosomes with no animal or human origin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eStable Shelf Life:\u003c\/strong\u003e Up to 3 years at 15–25°C.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 × 5ml vials per box.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOrigin:\u003c\/strong\u003e Spain (ES)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch4\u003e\u003cstrong\u003eWhy Elixir Aesthetics?\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cp\u003eElixir Aesthetics Inc. is a Canadian distributor of premium professional aesthetic solutions, specializing in exosome-based and regenerative skincare for licensed practitioners. Our formulations are selected for clinical efficacy, regulatory compliance, and practitioner confidence — so you can deliver measurable results for your clients.\u003c\/p\u003e\n\n\u003cp\u003e📦 \u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 × 5ml vials\u003c\/p\u003e","brand":"Elixir Aesthetics","offers":[{"title":"Default Title","offer_id":51763479609658,"sku":"Elixir-Exo","price":91.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/ElixirAestheticsCentellaExosomesBioRevitalizer5x5mlvials.jpg?v=1755777767"},{"product_id":"epicexosome-advanced-exosome-skincare-20-billion-verifiead-exosomes-starter-set","title":"EPICEXOSOME 20 Billion Bovine Milk Exosomes - Webinar Attendees Only","description":"\u003ch1\u003eEPICEXOSOME 20 Billion Exosomes Advanced Skin Care\u003c\/h1\u003e\n\u003cp data-start=\"1505\" data-end=\"1841\"\u003eEPICEXOSOME is a \u003cstrong data-start=\"1559\" data-end=\"1599\"\u003epremium cosmetic skincare innovation\u003c\/strong\u003e developed to visibly enhance skin’s appearance and promote a radiant, youthful look. Each vial contains over 20 billion bovine milk exosomes, blended with 4 encapsulated peptides and 370+ skin-supporting proteins, to deliver cosmetic benefits such as:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli data-start=\"1845\" data-end=\"1894\"\u003eVisibly improved skin elasticity and smoothness\u003c\/li\u003e\n\u003cli data-start=\"1897\" data-end=\"1949\"\u003eSupport for a brighter, more even-toned complexion\u003c\/li\u003e\n\u003cli data-start=\"1952\" data-end=\"1984\"\u003eEnhanced hydration and comfort\u003c\/li\u003e\n\u003cli data-start=\"1987\" data-end=\"2050\"\u003eReduction in the appearance of redness and visible irritation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-start=\"2052\" data-end=\"2225\"\u003eFormulated with \u003cstrong data-start=\"2068\" data-end=\"2145\"\u003eAsian Centella Exosomes, PDRN (Sodium DNA), Hyaluronate, stem cell extracts and antioxidants\u003c\/strong\u003e, EPICEXOSOME represents the next generation of \u003cstrong data-start=\"2193\" data-end=\"2222\"\u003escience-inspired skincare\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cp data-start=\"2227\" data-end=\"2293\"\u003e🌍 Proudly Canadian brand | Made in EU under sterile conditions.\u003cbr\u003e\u003cbr\u003e\u003cstrong data-start=\"755\" data-end=\"764\"\u003eNote:\u003c\/strong\u003e This is a cosmetic product intended for professional use. For the full product description and scientific details, please visit EPICEXOSOME official site: \u003ca data-start=\"917\" data-end=\"967\" rel=\"noopener\" class=\"decorated-link\" href=\"https:\/\/epicexosome.com\"\u003ehttps:\/\/epicexosome.com\u003c\/a\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp data-start=\"2227\" data-end=\"2293\"\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003cp data-start=\"2227\" data-end=\"2293\"\u003e \u003c\/p\u003e","brand":"EPICEXOSOME","offers":[{"title":"5 Boxes = 25 treatments —  $450\/box   Total $2250 CAD","offer_id":53027244081466,"sku":"EpicExo-5-Set","price":2250.0,"currency_code":"CAD","in_stock":true},{"title":"10 Boxes = 50 treatments —  $410\/box   Total $4100 CAD","offer_id":53027282813242,"sku":"EpicExo-5-Set","price":4100.0,"currency_code":"CAD","in_stock":true},{"title":"20 Boxes = 100 treatments —  $370\/box   Total $7400 CAD","offer_id":53027282846010,"sku":"EpicExo-5-Set","price":7400.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/EPICEXOSOME20BillionExosomesAdvancedSkinCare-2.jpg?v=1755520959"},{"product_id":"skinderma-exo-whitening-5-x-1500-ui","title":"SKINDERMA Lyophilized EXO-Whitening Exosome 5 X 1500 UI","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Lyophilized EXO-Whitening 5 x 1500 UI\u003c\/strong\u003e is a unique cosmetic formulation in \u003cstrong\u003elyophilized form\u003c\/strong\u003e — preserving the delicate bioactive structure of exosomes for maximum potency and stability. It combines three powerful active ingredients in a precise synergy specifically designed to address hyperpigmentation, dark spots, and uneven skin tone.\u003c\/p\u003e\n\u003cp\u003eThe lyophilized format ensures superior shelf stability and bioavailability compared to liquid formulations, making it the preferred choice for discerning aesthetic professionals.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly reduces the appearance of dark spots and hyperpigmentation\u003c\/li\u003e\n\u003cli\u003eHelps even out skin tone and brighten the complexion\u003c\/li\u003e\n\u003cli\u003eSupports skin clarity for melasma-prone skin\u003c\/li\u003e\n\u003cli\u003eDelivers a luminous, radiant skin booster effect\u003c\/li\u003e\n\u003cli\u003eSuperior potency preserved through freeze-drying technology\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGalactomyces Extracellular Vesicles\u003c\/strong\u003e — ferment-derived exosomes known for brightening and pore-refining properties\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLactobacillus Extracellular Vesicles\u003c\/strong\u003e — probiotic-derived exosomes that support skin microbiome balance and repair\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTranexamic Acid\u003c\/strong\u003e — clinically recognized ingredient that visibly reduces melanin production and dark spot appearance\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face \u0026amp; Neck\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Hyperpigmentation, dark spots, melasma, skin brightening booster\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 1500 UI lyophilized vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA Lyophilized Exo Whitening Exosome?\u003c\/strong\u003e SKINDERMA Lyophilized Exo Whitening is a professional-grade freeze-dried exosome brightening serum combining Galactomyces Extracellular Vesicles, Lactobacillus Extracellular Vesicles, and Tranexamic Acid. The lyophilized format preserves maximum bioactivity until the moment of use, delivering superior potency compared to standard liquid formulations for targeting hyperpigmentation, melasma, and dark spots.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is lyophilization and why does it matter?\u003c\/strong\u003e Lyophilization (freeze-drying) removes moisture from the formula while preserving the delicate bioactive structure of the exosomes. This results in a more stable, longer-lasting product with higher bioavailability — the active ingredients remain fully intact until reconstitution at the time of treatment.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does Exo Whitening target?\u003c\/strong\u003e This formula is clinically designed to address hyperpigmentation disorders, melasma, post-inflammatory dark spots, and uneven skin tone. Tranexamic Acid inhibits excess melanin production, while the exosome complex supports skin repair and microbiome balance for a brighter, more even complexion.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Lyophilized Exo Whitening is formulated for licensed aesthetic practitioners and clinics performing microneedling, mesotherapy, or brightening treatment protocols. It is intended for professional use in treating patients with pigmentation concerns.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":53143837802810,"sku":"SKD 2007","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/EXO-WHITENING_1500UI.jpg?v=1773263658"},{"product_id":"epicexosome-20-billion-bovine-milk-exosomes","title":"EPICEXOSOME 20 Billion Bovine Milk Exosomes – Dual Exosome Technology Skin Rejuvenation 5 Sets","description":"\u003cp\u003e\u003cstrong\u003eEPICEXOSOME\u003c\/strong\u003e is the world's first \u003cstrong\u003eDual Exosome Technology\u003c\/strong\u003e post-procedure system, uniquely combining \u003cstrong\u003eBovine Milk Exosomes\u003c\/strong\u003e and \u003cstrong\u003eCentella Asiatica (Asian Centella) Exosomes\u003c\/strong\u003e in a single advanced formula. Each vial contains over \u003cstrong\u003e20 billion lyophilized exosomes\u003c\/strong\u003e, freeze-dried to preserve their delicate bioactive structure and ensure maximum potency and stability.\u003c\/p\u003e\n\u003cp\u003eBlended with \u003cstrong\u003e4 encapsulated peptides\u003c\/strong\u003e, \u003cstrong\u003ePDRN\u003c\/strong\u003e, and \u003cstrong\u003e370+ skin-supporting proteins\u003c\/strong\u003e, EPICEXOSOME delivers next-generation cosmetic regeneration and recovery results for professional post-procedure skin care.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eKey Cosmetic Benefits:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVisibly improves skin elasticity and smoothness\u003c\/li\u003e\n\u003cli\u003eBrightens and evens skin tone\u003c\/li\u003e\n\u003cli\u003eDeeply hydrates and restores skin comfort\u003c\/li\u003e\n\u003cli\u003eReduces the appearance of redness and visible irritation\u003c\/li\u003e\n\u003cli\u003eSupports post-procedure skin recovery and regeneration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAdvanced Dual Exosome Formula:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e20 Billion Bovine Milk Exosomes (validated by Nanoparticle Tracking Analysis)\u003c\/li\u003e\n\u003cli\u003eCentella Asiatica Exosomes\u003c\/li\u003e\n\u003cli\u003ePDRN (Polydeoxyribonucleotide) | Hyaluronate | Stem Cell Extracts\u003c\/li\u003e\n\u003cli\u003e4 Encapsulated Peptides | 370+ Bioactive Proteins\u003c\/li\u003e\n\u003cli\u003eLyophilized (freeze-dried) for maximum preservation and potency\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIdeal for professional post-treatment protocols including \u003cstrong\u003emicroneedling, lasers, RF needling,\u003c\/strong\u003e and \u003cstrong\u003echemical peels\u003c\/strong\u003e. Formulated for aesthetic professionals seeking science-driven skin regeneration results.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 1 Box contains 5 Sets of EPICEXOSOME\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy Bovine Milk Exosomes?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eExosomes are nano-sized extracellular vesicles (30–150nm) secreted by cells to carry growth factors, microRNA, signaling proteins, and bioactive lipids between cells, functioning as the body’s intercellular communication system. Bovine Milk Exosomes are among the most biocompatible and biomimetically relevant exosome sources for human skin application: milk-derived exosomes are naturally abundant, scalable, and highly stable, and their surface protein profiles closely mirror those of human cell-derived exosomes, allowing them to be recognized and internalized by human skin cells with high efficiency. Bovine Milk Exosomes carry a rich natural cargo of growth factors, microRNA sequences, anti-inflammatory proteins, and regenerative signaling molecules that activate skin cell repair, collagen synthesis, and inflammation resolution, making them particularly effective for post-procedure recovery where the skin’s own regenerative signaling is overwhelmed. Each vial’s 20 billion exosome count is validated by Nanoparticle Tracking Analysis (NTA), the gold standard method for measuring exosome concentration and particle size distribution.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy the Dual Exosome Approach?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eEPICEXOSOME’s proprietary combination pairs Bovine Milk Exosomes (delivering growth factor and regenerative protein cargo) with Centella Asiatica Exosomes, plant-derived nano-vesicles carrying the concentrated bioactive triterpenoids of Centella (asiaticoside, madecassoside) in an exosome delivery format that dramatically enhances their cellular uptake compared to conventional botanical extract. The two exosome populations act synergistically: Bovine Milk Exosomes activate fibroblast regeneration and anti-inflammatory pathways, while Centella Exosomes deliver collagen-stimulating triterpenoids with enhanced dermal penetration. Together they address post-procedure recovery, collagen rebuilding, and inflammation resolution simultaneously.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is PDRN and why is it in this formula?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003ePDRN supports tissue comfort and skin renewal at a cellular level.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow to Use\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 1. Reconstitute:\u003c\/strong\u003e Open the vials. Pour the Centella Asiatica Exosome with PDRN Serum (solvent) into the lyophilized Bovine Milk Exosome vial. Gently swirl until fully dissolved. Do not shake.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 2. Cleanse \u0026amp; Prepare:\u003c\/strong\u003e Ensure the skin is clean and dry. If used post-procedure (after microneedling or laser), proceed immediately after while the skin is most receptive.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 3. Apply:\u003c\/strong\u003e Dispense the reconstituted serum with a sterile syringe. Apply evenly across the face and neck using gentle pressing motions. Avoid rubbing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 4. Absorb:\u003c\/strong\u003e Allow the serum to fully absorb. Do not rinse. Follow with your practice treatment protocol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStep 5. Frequency:\u003c\/strong\u003e Use as a standalone treatment or as part of your post-procedure recovery routine. One set per session is recommended. Optimal results develop with consistent use over 4–6 weeks.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNote:\u003c\/strong\u003e For full scientific details, visit the official EPICEXOSOME site: \u003ca href=\"https:\/\/epicexosome.com\"\u003ehttps:\/\/epicexosome.com\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e🍁 Proudly Canadian brand | Made in EU\u003c\/p\u003e","brand":"EPICEXOSOME","offers":[{"title":"Default Title","offer_id":53364833976634,"sku":"EpicExo-5-Set","price":700.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/EPICEXOSOME20BillionExosomesAdvancedSkinCare-2.jpg?v=1755520959"},{"product_id":"skinderma-ghk-cu-copper-peptide-microneedling-mesotherapy-serum","title":"SKINDERMA GHK-Cu Copper Peptide Microneedling Mesotherapy Serum","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA GHK-Cu Peptide Combo\u003c\/strong\u003e is a professional-grade bioactive serum formulated with Copper Tripeptide-1 (GHK-Cu), one of the most studied peptides in advanced aesthetic medicine for its multi-pathway skin rejuvenation properties.\u003c\/p\u003e\n\u003ch2\u003eKey Active Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate 1.00%\u003c\/strong\u003e — deep hydration and plumping\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium DNA 0.30%\u003c\/strong\u003e — cellular repair and skin resilience\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCopper Tripeptide-1 (GHK-Cu) 0.08%\u003c\/strong\u003e — collagen stimulation, tissue remodeling\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAcetyl Decapeptide-3 0.01%\u003c\/strong\u003e — complementary peptide synergy\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWhat It Targets\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVisible signs of photoaging and skin laxity\u003c\/li\u003e\n\u003cli\u003eLoss of firmness and elasticity\u003c\/li\u003e\n\u003cli\u003eUneven texture and dull complexion\u003c\/li\u003e\n\u003cli\u003eOxidative stress and inflammatory skin conditions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePresentation\u003c\/strong\u003e: 5 vials x 10ml\u003c\/p\u003e\n\u003ch2\u003eHow It Works\u003c\/h2\u003e\n\u003cp\u003eGHK-Cu activates fibroblast activity to support the natural production of Collagen I \u0026amp; III, Elastin, Glycosaminoglycans, and Proteoglycans — the structural proteins responsible for firm, resilient skin. It also promotes angiogenesis and tissue repair while modulating local inflammatory response.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIdeal For:\u003c\/strong\u003e Skin showing early to advanced signs of aging, photoaging, or requiring intensive dermal regeneration support.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp class=\"_p_1x4zg_107\"\u003e\u003cstrong\u003e\u003cspan\u003eWhat is GHK-Cu?\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e GHK-Cu (Copper Tripeptide-1) is a naturally occurring bioactive tripeptide-copper complex found in human plasma. It has been extensively studied for its ability to stimulate collagen synthesis, accelerate wound healing, and modulate inflammatory pathways — making it one of the most versatile actives in professional aesthetic medicine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"_p_1x4zg_107\"\u003e\u003cstrong\u003e\u003cspan\u003eWhat skin concerns does GHK-Cu address?\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e GHK-Cu is clinically recognized for addressing photoaging, skin laxity, loss of elasticity, rough texture, and dull or tired-looking skin. It is particularly effective for patients seeking dermal regeneration and improved overall skin quality.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"_p_1x4zg_107\"\u003e\u003cstrong\u003e\u003cspan\u003eWhat ingredients does GHK-Cu Peptide Combo contain?\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e This formula contains Copper Tripeptide-1 (GHK-Cu) 0.08%, Sodium DNA 0.30%, Sodium Hyaluronate 1.00%, and Acetyl Decapeptide-3 0.01% — a synergistic complex designed to maximize cellular repair, hydration, and structural skin renewal.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"_p_1x4zg_107\"\u003e\u003cstrong\u003e\u003cspan\u003eWho is this serum for?\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e GHK-Cu Peptide Combo is formulated for licensed aesthetic practitioners treating patients with early to advanced signs of aging, photoaging, or those requiring intensive dermal regeneration support.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"_p_1x4zg_107\"\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use. Intended for licensed aesthetic practitioners.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":53685896741178,"sku":"SKD 1158","price":308.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/SKINDERMAGHK-Cu-PeptideCombo1.png?v=1783229469"},{"product_id":"skinderma-nad-coenzyme-skin-rejuvenation-microneedling-mesotherapy-serum","title":"SKINDERMA NAD+ Coenzyme Skin Rejuvenation Microneedling Mesotherapy Serum","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA NAD+ Skin Rejuvenation Vials\u003c\/strong\u003e deliver a professional-grade coenzyme complex designed to restore cellular energy, combat photoaging, and visibly revitalize tired, dull, or dehydrated skin. Presented as 10 ml × 5 vials for precise, hygienic application.\u003c\/p\u003e\n\u003ch2\u003eKey Active Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eNicotinamide Adenine Dinucleotide (NAD⁺) 5%\u003c\/strong\u003e — essential coenzyme for ATP energy production, DNA repair, and cellular longevity; supports skin regeneration at a metabolic level\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDimethylaminoethanol (DMAE) 1%\u003c\/strong\u003e — improves skin tone and firmness; associated with a visible lifting effect and correction of mild sagging\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate 1%\u003c\/strong\u003e — high water-retention capacity for deep hydration and improved elasticity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBoosts cellular energy and metabolism\u003c\/li\u003e\n\u003cli\u003eIncreases skin hydration and radiance\u003c\/li\u003e\n\u003cli\u003eProvides antioxidant protection against environmental stressors\u003c\/li\u003e\n\u003cli\u003eImproves firmness and skin tone\u003c\/li\u003e\n\u003cli\u003eSupports post-treatment skin recovery\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eIdeal For\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTired, dull, or dehydrated skin\u003c\/li\u003e\n\u003cli\u003ePremature and photoaging concerns\u003c\/li\u003e\n\u003cli\u003ePost-treatment care and skin recovery\u003c\/li\u003e\n\u003cli\u003eThin, sensitive skin or areas with more advanced aging signs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 10 ml × 5 vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is NAD+?\u003c\/strong\u003e NAD⁺ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme present in every living cell, responsible for driving energy production (ATP), facilitating DNA repair, and regulating cellular longevity. In aesthetic medicine, NAD⁺ is recognized for its role in restoring cellular metabolism and supporting skin regeneration from within.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does NAD+ address?\u003c\/strong\u003e NAD⁺ Skin Rejuvenation Vials are clinically formulated to address tired and dull skin, dehydration, premature aging, photoaging, and post-treatment recovery. The formula targets cellular energy depletion — a root cause of visible skin aging.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat ingredients does SKINDERMA NAD+ contain?\u003c\/strong\u003e This formula contains Nicotinamide Adenine Dinucleotide (NAD⁺) 5%, Dimethylaminoethanol (DMAE) 1%, and Sodium Hyaluronate 1% — a synergistic complex that revitalizes cellular energy, improves firmness, and delivers deep hydration.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this serum for?\u003c\/strong\u003e SKINDERMA NAD+ Vials are designed for licensed aesthetic practitioners treating patients with signs of skin fatigue, photoaging, dehydration, or those requiring post-treatment recovery support. Suitable for thin, sensitive skin and areas showing more advanced aging.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use. Intended for licensed aesthetic practitioners.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":53685899395386,"sku":"SKD 1157","price":332.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/SKINDERMANAD_1.png?v=1783227814"},{"product_id":"bio-needle-24-adjustable-needle-length","title":"Bio Needle 24 - Adjustable Needle Length","description":"\u003ch1\u003eBio Needle 24 - Adjustable Needle Length\u003c\/h1\u003e\n\u003ch5\u003e\u003cbr\u003e\u003c\/h5\u003e\n\u003ch5\u003eNeedle Depth 0 - 1.5mm\u003c\/h5\u003e\n\u003cp\u003eThe Bio Needle 24 provides users with the flexibility to select the optimal needle depth based on their skin type and the targeted treatment area, catering to various skincare concerns. For example, shorter needle depths may be chosen for the forehead and eye area, while longer depths are suitable for the cheeks and body. With 24 titanium needles, it offers the option to choose different mesotherapy cocktails to address specific skin concerns.\u003c\/p\u003e\n\u003ch5\u003eEvenly \u0026amp; Efficiently\u003c\/h5\u003e\n\u003cp\u003eIntroduce your chosen mesotherapy serum, adjust the needle length using the knob, and lightly tap on the skin. As the Bio Needle 24 operates on the skin's surface, the mesotherapy serum will be evenly dispensed through the 24 tiny holes and central axis, following the needles to reach various skin layers. The Bio Needle 24 is compatible with a variety of mesotherapy skin serums, effectively addressing various skin concerns.\u003c\/p\u003e\n\u003ch5\u003eHygienic and Dual Protection\u003c\/h5\u003e\n\u003cp\u003eThe plastic cover ensures the cleanliness and safety of the needles and the glass vial. The glass vial is detachable and can be replaced with any standard glass vial available on the market. However, we do not recommend reusing the needle.\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"size-full wp-image-45084 lazyload\" alt=\"Bio Needle 24\" width=\"2560\" height=\"1440\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 2560px; --smush-placeholder-aspect-ratio: 2560\/1440;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg class=\"size-full wp-image-45089 lazyload\" alt=\"Bio Needle 24 Package\" width=\"1000\" height=\"1000\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1000px; --smush-placeholder-aspect-ratio: 1000\/1000;\"\u003e\u003c\/p\u003e","brand":"Mesotherapy.ca","offers":[{"title":"Default Title","offer_id":53815014359354,"sku":"BIO-NEEDLE-24","price":35.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/Microneedling-stamp-Bio-needle-H24-3.jpg?v=1790139485"},{"product_id":"skinderma-panthenol-vitamin-b5-microneedling-mesotherapy-ampoules","title":"SKINDERMA Panthenol Vitamin B5 5% Microneedling Mesotherapy Ampoules","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Panthenol Vitamin B5 5% 20 x 5ml\u003c\/strong\u003e is a professional-grade skin conditioning and barrier restoration mesotherapy ampoule, formulated with 5% Panthenol — the most bioavailable and skin-active form of Vitamin B5. Designed for use in microneedling and mesotherapy protocols, it delivers deep, lasting hydration, accelerates skin barrier repair, and reduces inflammation at the cellular level, making it an essential foundational active across skin rejuvenation, skin recovery, and scalp health protocols.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDelivers deep, long-lasting hydration by increasing skin moisture content\u003c\/li\u003e\n\u003cli\u003eRestores and reinforces the skin barrier for improved resilience and protection\u003c\/li\u003e\n\u003cli\u003eReduces inflammation and calms sensitized or compromised skin\u003c\/li\u003e\n\u003cli\u003eImproves skin elasticity, softness, and suppleness\u003c\/li\u003e\n\u003cli\u003eSupports epithelial trophic activity and healthy lipid metabolism\u003c\/li\u003e\n\u003cli\u003ePromotes scalp health and supports protocols addressing seborrheic scalp conditions\u003c\/li\u003e\n\u003cli\u003eVersatile foundational active compatible with anti-aging, skin recovery, and scalp protocols\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePanthenol (Provitamin B5) 5%\u003c\/strong\u003e — a water-soluble alcohol analog of pantothenic acid (Vitamin B5) and the most skin-compatible, bioavailable form of B5 for professional aesthetic use. Once absorbed into the skin, Panthenol is enzymatically converted to pantothenic acid, which is a critical component of Coenzyme A (CoA) — the central metabolic cofactor involved in fatty acid synthesis, cellular energy production (via the Krebs cycle), and the biosynthesis of ceramides and other essential lipids that form the skin’s protective barrier. This conversion is the mechanistic foundation of Panthenol’s broad skin benefits. As a humectant, Panthenol attracts and binds water molecules within the stratum corneum and dermis, significantly increasing skin hydration and maintaining moisture balance in dehydrated or compromised skin. As a barrier repair agent, Panthenol stimulates the synthesis of ceramides and structural proteins in keratinocytes, reinforcing the intercellular lipid matrix of the skin barrier and reducing transepidermal water loss (TEWL). Its anti-inflammatory mechanism involves inhibition of NF-κB-mediated pro-inflammatory cytokine release, reducing redness, sensitization, and inflammatory damage in both skin recovery and chronically compromised barrier conditions. Panthenol also supports epithelial proliferation — stimulating keratinocyte migration and division — which accelerates wound healing and skin renewal. At the scalp level, Panthenol’s barrier-restoring and anti-inflammatory properties support a healthy follicle microenvironment, making it beneficial in protocols addressing seborrheic scalp conditions and scalp inflammation associated with hair thinning.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face, Neck, Body \u0026amp; Scalp\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Dehydrated skin, compromised skin barrier, skin recovery protocols, inflammation, seborrheic scalp conditions, anti-aging protocols\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is SKINDERMA Panthenol Vitamin B5 and what is it used for?\u003c\/strong\u003e SKINDERMA Panthenol Vitamin B5 5% is a professional mesotherapy and microneedling ampoule containing 5% Panthenol — the provitamin form of Vitamin B5. It is used in professional aesthetic protocols to deliver deep hydration, restore the skin barrier, reduce inflammation, and support skin renewal on the face, neck, body, and scalp. It is a foundational active in skin recovery, dehydrated and sensitized skin protocols, and scalp health treatments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHow does Panthenol restore the skin barrier?\u003c\/strong\u003e Once absorbed, Panthenol converts to pantothenic acid, which drives Coenzyme A synthesis. CoA is essential for ceramide and lipid biosynthesis in keratinocytes — the building blocks of the skin’s intercellular lipid matrix. By supporting ceramide production, Panthenol directly reinforces the structural integrity of the skin barrier, reduces transepidermal water loss (TEWL), and restores the skin’s ability to retain moisture and resist external irritants.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is Panthenol effective for skin recovery protocols?\u003c\/strong\u003e Skin that has undergone professional treatments such as microneedling, laser, chemical peels, or RF has a temporarily compromised barrier and elevated inflammation. Panthenol addresses both simultaneously: its humectant action restores moisture to dehydrated skin, its barrier-repair activity accelerates the rebuilding of the damaged stratum corneum, and its anti-inflammatory mechanism — inhibiting NF-κB cytokine release — calms redness and sensitization. It also stimulates keratinocyte proliferation to accelerate tissue renewal, shortening recovery time and improving skin outcomes.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is the role of Panthenol in scalp and hair protocols?\u003c\/strong\u003e At the scalp level, Panthenol’s barrier-restoring and anti-inflammatory properties support a healthy follicle microenvironment by reducing scalp inflammation, improving hydration of the scalp dermis, and supporting the trophic activity of the epithelium surrounding the follicle. These mechanisms make it particularly effective in protocols addressing seborrheic scalp conditions, scalp sensitization, and inflammatory states associated with hair thinning and follicle stress.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Panthenol Vitamin B5 5% is formulated for licensed aesthetic practitioners, dermatologists, trichologists, and skin clinics performing professional microneedling, mesotherapy, and skin recovery protocols. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":54071494213946,"sku":"SKD 1050","price":90.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/panthenol.jpg?v=1789852982"},{"product_id":"skinderma-cellulite-combo-5-x-10ml","title":"SKINDERMA Cellulite Combo 5 X 10ml","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Cellulite Combo 5 x 10ml\u003c\/strong\u003e is a powerful multi-ingredient anti-cellulite microneedling mesotherapy cocktail designed to treat spongy and oedematous cellulite and help reshape the silhouette. Its synergistic formula targets fatty cellulite, fluid retention, and skin laxity through five complementary mechanisms of action — delivering comprehensive results that single-ingredient protocols cannot match.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eTargets and visibly reduces spongy and oedematous cellulite\u003c\/li\u003e\n\u003cli\u003eHelps reshape and remodel areas affected by fatty cellulite\u003c\/li\u003e\n\u003cli\u003eSupports skin firming and tightening\u003c\/li\u003e\n\u003cli\u003eReduces fluid retention and improves lymphatic drainage\u003c\/li\u003e\n\u003cli\u003eIdeal for weight loss and body contouring programs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredients\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eL-Carnitine\u003c\/strong\u003e — an amino acid derivative that serves as the essential transporter of long-chain fatty acids into the mitochondria for energy production via beta-oxidation. In cellulite treatment, L-Carnitine accelerates the metabolic clearance of fatty acids released from adipocytes, supporting fat mobilization, reducing localized fat volume, and improving body contour over a course of treatments.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCaffeine\u003c\/strong\u003e — a methylxanthine that inhibits phosphodiesterase, causing an increase in intracellular cAMP levels in adipocytes. This activates hormone-sensitive lipase, stimulating lipolysis (fat breakdown) directly within fat cells. Caffeine also improves local microcirculation and lymphatic drainage, helping to reduce the fluid accumulation and vascular stasis that contribute to oedematous cellulite.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGlaucine\u003c\/strong\u003e — an isoquinoline alkaloid derived from Glaucium flavum (yellow horned poppy) with potent anti-inflammatory and anti-fibrotic properties that make it particularly valuable in cellulite treatment. Cellulite in advanced stages is characterized by fibrous septae — collagen bands that tether the skin downward, creating the dimpled appearance. Glaucine inhibits the activation of myofibroblasts and reduces the production of pro-fibrotic TGF-β1 signaling, softening existing fibrous septae and preventing further fibrotic remodeling of the connective tissue. This anti-fibrotic action directly addresses the structural root cause of fibrotic cellulite that other lipolytic agents cannot target.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylsilanol Mannuronate (Organic Silicium)\u003c\/strong\u003e — a marine-derived bioavailable form of silicon that stimulates fibroblast activity and reinforces collagen and elastin cross-linking in the extracellular matrix, improving skin elasticity, firmness, and tone in treated body areas.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCentella Asiatica Extract\u003c\/strong\u003e — a clinically recognized botanical active containing triterpenoids (asiaticoside, madecassoside, asiatic acid) that stimulate fibroblast proliferation and collagen type I and III synthesis, support microvascular integrity, and have anti-inflammatory properties. In anti-cellulite protocols, Centella Asiatica supports the restructuring of the dermal matrix and improves skin quality in areas affected by cellulite-related connective tissue degradation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Body\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Cellulite (spongy, oedematous, fibrotic), weight loss programs, skin firming, fluid retention\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 10ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat makes SKINDERMA Cellulite Combo more effective than single-ingredient lipolytic treatments?\u003c\/strong\u003e  Cellulite is a multi-factorial condition involving excess fat accumulation, poor microcirculation, fluid retention, and fibrotic connective tissue septae. Single-ingredient treatments typically address only one of these factors. Cellulite Combo targets all four simultaneously — L-Carnitine and Caffeine address fat metabolism and lipolysis, Glaucine targets the fibrotic septae causing skin dimpling, Methylsilanol Mannuronate firms the overlying skin, and Centella Asiatica supports connective tissue restructuring and microvascular health.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat is Glaucine and why is it important for cellulite treatment?\u003c\/strong\u003e  Glaucine is an isoquinoline alkaloid from Glaucium flavum with anti-fibrotic properties that directly address fibrotic cellulite — the most structurally resistant form. Advanced cellulite involves fibrous collagen bands (septae) that tether skin to deeper tissue, causing the characteristic dimpling. Glaucine inhibits myofibroblast activation and reduces TGF-β1-driven fibrotic remodeling, softening these septae and addressing the structural root cause of cellulite that lipolytic-only protocols cannot treat.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat types of cellulite does this formula treat?\u003c\/strong\u003e  Cellulite Combo is effective across all major cellulite types: spongy\/oedematous cellulite (where fluid retention and poor circulation are primary factors, addressed by Caffeine and Centella), fatty cellulite (addressed by L-Carnitine and Caffeine-driven lipolysis), and fibrotic cellulite (addressed by Glaucine’s anti-fibrotic mechanism). Its multi-pathway approach makes it suitable as a foundational protocol for any cellulite presentation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Cellulite Combo is formulated for licensed aesthetic practitioners, dermatologists, and body contouring specialists performing anti-cellulite mesotherapy and microneedling protocols. \u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":54110421680442,"sku":"SKD 1087","price":105.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/celluite.jpg?v=1790148376"},{"product_id":"skinderma-hyaluronic-acid-1-sterile-microneedling-mesotherapy-cocktail","title":"SKINDERMA Hyaluronic Acid 1% Sterile Microneedling Mesotherapy Cocktail","description":"\u003cp\u003e\u003cstrong\u003eSKINDERMA Hyaluronic Acid 1% 5 x 5ml\u003c\/strong\u003e is a professional-grade microneedling mesotherapy vial delivering an intensive concentration of Sodium Hyaluronate directly into the skin. At 1%, this high-potency formula deeply replenishes and maintains the skin’s moisture levels, restoring a plump, supple, and youthful appearance.\u003c\/p\u003e\n\u003ch2\u003eKey Benefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eDeeply hydrates and plumps dry, dehydrated skin\u003c\/li\u003e\n\u003cli\u003eVisibly reduces the appearance of wrinkles and expression lines\u003c\/li\u003e\n\u003cli\u003eImproves skin elasticity and firmness\u003c\/li\u003e\n\u003cli\u003eSupports tissue restructuring and repair of damaged skin\u003c\/li\u003e\n\u003cli\u003eHelps slow the visible signs of aging by supporting fibroblast activity and collagen formation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eActive Ingredient\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSodium Hyaluronate (1%)\u003c\/strong\u003e — the sodium salt form of hyaluronic acid, naturally present in the dermis and responsible for maintaining skin hydration, volume, and structural integrity. Sodium Hyaluronate has an extraordinary water-retention capacity — binding up to 1,000 times its own weight in water — making it the most effective natural humectant available in aesthetic medicine. At 1% professional concentration, delivered intradermally via mesotherapy or microneedling, it provides a level of dermal hydration that topical HA formulations cannot achieve, as they are unable to penetrate to the depth of the dermis. Beyond hydration, Sodium Hyaluronate at this concentration also stimulates fibroblast activity and collagen synthesis, improving skin density, elasticity, and firmness over a course of treatments. The result is visibly plumper, smoother, more resilient skin with reduced wrinkle depth and improved overall skin quality.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Dry and aging skin, dehydrated skin, wrinkles and expression lines\u003cbr\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e 5 x 5ml vials\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat makes SKINDERMA Hyaluronic Acid 1% different from topical HA serums?\u003c\/strong\u003e Topical hyaluronic acid serums act primarily on the skin surface, as HA molecules are too large to penetrate the dermis effectively. SKINDERMA HA 1%, delivered intradermally via mesotherapy or microneedling, bypasses this barrier entirely — depositing a high concentration of Sodium Hyaluronate directly into the dermis where it can bind water, restore volume, and stimulate fibroblasts and collagen synthesis at the cellular level. The result is deep, lasting hydration that topical products cannot replicate.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhy is 1% a significant HA concentration for mesotherapy?\u003c\/strong\u003e Most skin booster products and HA mesotherapy vials contain between 0.5% and 2% Sodium Hyaluronate. At 1%, SKINDERMA delivers a markedly higher hyaluronic acid load per treatment session, providing more intensive hydration, more pronounced plumping and volume restoration, and a stronger stimulus for fibroblast activity and collagen production — making it particularly suited for dehydrated, mature, or environmentally damaged skin requiring intensive rejuvenation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWhat skin concerns does HA 1% mesotherapy treat?\u003c\/strong\u003e This formula is recommended for dry and chronically dehydrated skin, fine lines and wrinkles caused by moisture loss, loss of skin elasticity and firmness, dull and tired-looking skin, and post-procedure skin recovery. It is also used as a foundational hydration step in combination mesotherapy protocols alongside peptides, vitamins, and regenerative actives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eWho is this product for?\u003c\/strong\u003e SKINDERMA Hyaluronic Acid 1% is formulated for licensed aesthetic practitioners, dermatologists, and skin clinics performing professional microneedling and mesotherapy hydration and rejuvenation protocols. It is intended for professional clinic use only.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eFor professional use only. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":67617192771898,"sku":"SKD 1063","price":118.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/hyaluronicacid_s.jpg?v=1755602573"},{"product_id":"skinderma-oligoelements-5ml","title":"SKINDERMA OligoElements Trace Mineral Microneedling Mesotherapy Ampoules","description":"\u003ch2\u003eSKINDERMA OligoElements Trace Mineral Ampoules, 20 x 5ml\u003c\/h2\u003e\n\u003cp\u003eSKINDERMA OligoElements is a professional microneedling and mesotherapy serum with trace elements. Trace elements are necessary for the healthy functioning of the skin and have important qualities for maintaining a youthful appearance. OligoElements ampoules include substances that control and rebalance the condition of the skin. They are used as aids in the treatment of cellulite, localised fat, flaccidity, skin ageing and lesions.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eZinc: excellent antioxidant, aids in the healing process\u003c\/li\u003e\n\u003cli\u003eStrengthens and rebalances the skin's defenses against external aggressions\u003c\/li\u003e\n\u003cli\u003ePart of SKINDERMA hydration and acne mesotherapy protocols\u003c\/li\u003e\n\u003cli\u003eAlso used in hair loss mesotherapy protocols\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eMain Ingredients:\u003c\/strong\u003e Glucose 5%, Cobalt Gluconate 0.01%, Zinc Gluconate 0.005%, Nickel Gluconate 0.005%.\u003cbr\u003e\n\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Anti-aging, mineral supplement.\u003cbr\u003e\n\u003cstrong\u003eApplication:\u003c\/strong\u003e Microneedling and mesotherapy.\u003cbr\u003e\n\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face, neck and hair.\u003cbr\u003e\n\u003cstrong\u003ePresentation:\u003c\/strong\u003e 20 x 5ml ampoules.\u003cbr\u003e\n\u003cstrong\u003eBrand:\u003c\/strong\u003e SKINDERMA, made in Spain.\u003c\/p\u003e\n\u003cp\u003eFor licensed aesthetic professionals.\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":67636857209146,"sku":"SKD 1048","price":90.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/oligoelements.jpg?v=1791273717"},{"product_id":"skinderma-glutathione-20-ampoules-20-x-5ml","title":"SKINDERMA Glutathione 20% ampoules 20 x 5ml","description":"\u003cul\u003e\n\u003cli\u003e20% Glutathione, a powerful antioxidant\u003c\/li\u003e\n\u003cli\u003eHelps fade the look of melasma, dark spots and hyperpigmentation\u003c\/li\u003e\n\u003cli\u003eBrightens dull skin and evens out skin tone\u003c\/li\u003e\n\u003cli\u003eSterile ampoules for professional mesotherapy and microneedling\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e Box of 20 ampoules | Each ampoule 5ml | Mesotherapy Serum.\u003c\/p\u003e\u003ch2\u003eSKINDERMA Glutathione 20% Mesotherapy Ampoules\u003c\/h2\u003e\u003cp\u003eGlutathione is a powerful antioxidant that the body produces naturally. SKINDERMA Glutathione delivers 20% glutathione in sterile 5ml ampoules for professional skin brightening mesotherapy. It helps reduce melanin production by blocking tyrosinase, the enzyme skin uses to make pigment. This makes it a key active in melasma and depigmentation treatments.\u003c\/p\u003e\u003ch3\u003eBenefits\u003c\/h3\u003e\u003cul\u003e\n\u003cli\u003eHelps fade the look of melasma, dark spots and sun spots\u003c\/li\u003e\n\u003cli\u003eBrightens dull, tired-looking skin\u003c\/li\u003e\n\u003cli\u003eEvens out skin tone\u003c\/li\u003e\n\u003cli\u003eAntioxidant protection against free radicals\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003eTreatment Area:\u003c\/strong\u003e Face and neck.\u003cbr\u003e\u003cstrong\u003eRecommended For:\u003c\/strong\u003e Melasma, hyperpigmentation, sun spots, post-acne marks, dull skin.\u003cbr\u003e\u003cstrong\u003eActive Ingredient:\u003c\/strong\u003e Glutathione 20%.\u003c\/p\u003e\u003ch3\u003eProfessional Mesotherapy Protocol\u003c\/h3\u003e\u003col\u003e\n\u003cli\u003eCleanse and tone the skin.\u003c\/li\u003e\n\u003cli\u003eApply SKINDERMA Salicylic Exfoliator with gauze. No need to remove it.\u003c\/li\u003e\n\u003cli\u003ePut on gloves and prepare the needle and syringe.\u003c\/li\u003e\n\u003cli\u003eApply by nappage or point-by-point technique, following the protocol.\u003c\/li\u003e\n\u003cli\u003eFinish with a hydrating cream.\u003c\/li\u003e\n\u003c\/ol\u003e\u003ch3\u003eProfessional Microneedling Protocol\u003c\/h3\u003e\u003col\u003e\n\u003cli\u003eRemove make-up, cleanse and tone the skin.\u003c\/li\u003e\n\u003cli\u003eApply SKINDERMA Salicylic Exfoliator with gauze. No need to remove it.\u003c\/li\u003e\n\u003cli\u003ePut on gloves and place sterile single-use needles in the device.\u003c\/li\u003e\n\u003cli\u003eApply one ampoule to the treatment area with a small brush or pipette.\u003c\/li\u003e\n\u003cli\u003eTreat with the microneedling device: maximum 10 minutes and 2 passes per area.\u003c\/li\u003e\n\u003cli\u003eIf an area is very irritated, gently spread one ampoule of SKINDERMA Laureth-9 over it with gauze.\u003c\/li\u003e\n\u003cli\u003eApply a moisturizing mask for 15 minutes.\u003c\/li\u003e\n\u003cli\u003eApply the cream for the treatment.\u003c\/li\u003e\n\u003cli\u003eFinish with SPF Protector 50+. This step is required.\u003c\/li\u003e\n\u003c\/ol\u003e\u003cp\u003eThe number of sessions is set by the professional. Daily sunscreen SPF 30 or higher is required during treatment.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePresentation:\u003c\/strong\u003e Box of 20 ampoules, 5ml each. Made in Spain. For professional use only.\u003c\/p\u003e\u003cp\u003e\u003cem\u003eNot intended to diagnose, treat, cure, or prevent any disease.\u003c\/em\u003e\u003c\/p\u003e","brand":"SKINDERMA","offers":[{"title":"Default Title","offer_id":67766965436730,"sku":"SKD 1059","price":100.4,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0959\/9510\/1498\/files\/glutathione.jpg?v=1792715080"}],"url":"https:\/\/zviczv-1p.myshopify.com\/collections\/microneedling.oembed?page=3","provider":"Mesotherapy.ca","version":"1.0","type":"link"}